Synopsis of recent research by authors named "Zhen-Ya Gao"
- Zhen-Ya Gao's research primarily focuses on understanding the molecular mechanisms involved in eye-related diseases, particularly the apoptosis of retinal cells and the role of bone morphogenetic proteins in scleral fibroblast differentiation.
- Key findings include the identification of all-trans retinoic acid's ability to increase apoptosis in ARPE-19 cells through the activation of reactive oxygen species and endoplasmic reticulum stress pathways, indicating potential therapeutic implications.
- Gao's work also highlights the significance of the ASPM gene in bladder cancer prognosis and cellular proliferation, as well as the impact of certain compounds like 7-methylxanthine on myopia progression in animal models, underscoring the multifaceted nature of developmental and pathological processes in ocular health.
