Publications by authors named "Zhen-Xi Geng"
Trends Pharmacol Sci
August 2024
Article Synopsis
- PANoptosis is a specialized immune response that leads to a specific type of cell death, driven by sensors and proteins called caspases and RIPKs, which cannot be blocked by targeting other cell death methods like pyroptosis or apoptosis.
- This pathway is crucial for understanding certain diseases, particularly cancer and infections, but its role in cardiovascular diseases has been overlooked until now.
- The review highlights evidence of PANoptosis in various cardiovascular conditions and discusses potential therapeutic agents that could target this pathway as a new strategy for treatment.
