Publications by authors named "Zhen-Sen Chen"
Objectives: Sepsis can cause myocardial injury, which is one of the leading causes of death in critically ill patients. Fish oil rich in omega-3 polyunsaturated fatty acids (PUFAs) in ultralong chains has immunomodulatory effects and can inhibit the production of various critically ill proinflammatory cytokines. Therefore, this study focused on whether ω-3 PUFAs have a protective effect on sepsis-induced cardiomyopathy (SIC).
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- Sepsis, a serious infection-related organ dysfunction, poses a major public health issue in China, prompting a study to assess its frequency and mortality rates.
- After reviewing 846 studies, 29 were included, revealing a pooled sepsis frequency of 33.6% and mortality rates of 29.0% for sepsis, 31.1% for severe sepsis, and 37.3% for septic shock.
- The results indicate that sepsis and septic shock occurrences in China are notably higher than those in North America and Europe, highlighting an urgent need for more healthcare resources and further research in this field.
Decreased serum thyroid hormone levels and their prediction of mortality in septic patients are still controversial, especially with the evolution of the definition of sepsis. This study aimed to assess the ability of thyroid hormone disorders to predict the early mortality of patients with septic shock defined by Sepsis-3. Sixty-three adult patients with septic shock admitted to a university hospital emergency intensive care unit (EICU) were studied.
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