Publications by authors named "Zhen-Kai Ma"

Purpose: To investigate the effect of sub-satisfactory stenting recanalization of severe vascular stenosis of the posterior circulation on cerebral hemodynamic perfusion.

Materials And Methods: Patients with severe vascular stenosis of the posterior circulation who had undergone three-dimensional cerebral angiography before and after stenting were retrospectively enrolled. Computational fluid dynamic (CFD) analysis of hemodynamic parameters at the stenosis, perforating branch, and normal arterial segments proximal and distal to the stenosis were performed.

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Purpose: To investigate the safety and efficacy of Enterprise stent angioplasty and risk factors for the prognoses in treating symptomatic severe posterior circulation atherosclerotic stenosis (SSPCAS).

Materials And Methods: Patients with SSPCAS who were treated with the Enterprise stent angioplasty were retrospectively enrolled. The clinical data, peri-procedural complications, postoperative residual stenosis, in-stent restenosis and recurrent stroke at follow-up were analyzed.

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Purpose: The study aimed to investigate the safety, effect, and risk factors of endovascular recanalization of symptomatic non-acute occlusion of the vertebrobasilar artery (SNOVA).

Materials And Methods: Patients with SNOVA were retrospectively enrolled and treated with endovascular recanalization. The clinical data, endovascular treatment, peri-procedural complications, and follow-up outcomes were analyzed.

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Article Synopsis
  • The study evaluates the outcomes of esophagectomy combined with extended 2-field lymph node dissection in 1,690 patients with esophageal cancer from 1987 to 2008.
  • Lymph node metastasis was observed in 42.2% of patients, with significant rates in both thoracic and abdominal areas, while postoperative complications occurred in 16.4% of cases, primarily pulmonary issues.
  • Survival rates were reported at 88.2% for one year, decreasing to 30.8% by ten years, with a notable disparity between patients with and without lymph node metastasis in terms of survival.
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Background & Objective: As one of the principal causes of gene inactivation, aberrant hypermethylation in the promoter of cancer-related genes has attracted more and more attention. However, such studies on esophageal cancer are still limited. This study was to investigate the association between aberrant hypermethylation of MGMT gene and clinical characteristics as well as MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma in a Chinese population.

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Article Synopsis
  • - This study examines how regional lymph node metastasis affects the prognosis of thoracic esophageal carcinoma and seeks to establish guidelines for lymphadenectomy during the Ivor-Lewis procedure.
  • - Analyzing data from 1,412 patients, the study found that 38.74% had lymph node metastasis, with varying rates depending on the lymph node location and tumor stage, showing significantly higher rates in advanced-stage patients.
  • - The research highlights the importance of proper lymphadenectomy to improve surgical outcomes and provides insights on which lymph nodes are most affected by metastasis.
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Objective: To investigate the incidence of lymph node metastasis (LNM) in the right para-tracheal triangle (RPT) of esophageal carcinoma patients and the technique of dissection.

Methods: On the top of double mediastinal and abdominal lymphadenectomy, 333 esophageal carcinoma patients received RPT lymphadenectomy through the right pleural apical approach from 1990 to 2001.

Results: In these 333 patients, the lymph node metastasis (LNM) rate in the RPT was 36.

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Synopsis of recent research by authors named "Zhen-Kai Ma"

  • - Zhen-kai Ma's recent research focuses on endovascular treatments for severe vascular stenosis and occlusions in the posterior circulation, emphasizing their impact on cerebral hemodynamic perfusion and patient safety outcomes.
  • - A significant finding from his studies indicates that even suboptimal stenting techniques can lead to substantial improvements in cerebral blood flow, highlighting the potential benefits of stenting in high-risk vascular conditions.
  • - Additionally, his work discusses the efficacy of various stent types (such as the Enterprise stent) in treating symptomatic atherosclerotic stenosis, analyzing patient outcomes and complications, which provides valuable insights into the management of vascular diseases.