Publications by authors named "Zhen-Huan Zhang"

Article Synopsis
  • A study was conducted to assess the prevalence of a zoonotic intestinal protozoan in sheep and pigs in Shanxi province, indicating serious public health concerns.
  • Out of 492 sheep and 362 pig fecal samples, the protozoan was found in 16.26% of sheep and 14.09% of pigs, with subtype ST5 being the most common in both species.
  • The research enhances understanding of the genetic structure and potential zoonotic risks of these subtypes, highlighting the importance of monitoring animal health for public safety.
View Article and Find Full Text PDF

Enterocytozoon bieneusi is an intracellular pathogen that can parasitize humans and a variety of animals. The infection of E. bieneusi in most hosts is asymptomatic, but in immunocompromised individuals, it can lead to serious complications such as acute diarrhea, dehydration, and even death.

View Article and Find Full Text PDF

is a common opportunistic intestinal pathogen that can cause acute diarrhea in immunosuppressed humans and animals. Though has been widely detected in pigs around the world, little is known of its prevalence and genotype distribution in pigs in Shanxi province, north China. In this study, a total of 362 fecal samples were collected from pigs in three representative counties in north, south, and central Shanxi province, China.

View Article and Find Full Text PDF
Article Synopsis
  • Enterocytozoon bieneusi is a fungus-like protist causing malabsorption and diarrhea in animals and humans, posing risks to animal husbandry and public health; its prevalence in sheep in Shanxi Province, North China was previously unknown.
  • In a study involving 492 fecal samples from sheep across three counties, a 34.2% prevalence of E. bieneusi was found, with significant regional differences but no notable differences by gender or age.
  • Five genotypes were identified, including four known and one new genotype, with BEB6 being the most common; this research offers a foundation for future efforts to control E. bieneusi infections in both sheep and humans.
View Article and Find Full Text PDF

The purpose of this study is to measure, characterize, and compare the viscoelastic properties of the posterior eye of advanced dry age-related macular degeneration (AMD) patients, age-matched normal subjects, and pigs (3 groups). Ten horizontal and ten vertical strips of the macula retina and the underneath choroid and sclera were obtained for each group, respectively. They were examined by incremental stress-relaxation cycles in body-temperature saline.

View Article and Find Full Text PDF

Cell-free circulating DNA (cf-DNA) can be detected by various of laboratory techniques. We described a branched DNA-based Alu assay for measuring cf-DNA in septic patients. Compared to healthy controls and systemic inflammatory response syndrome (SIRS) patients, serum cf-DNA levels were significantly higher in septic patients (1426.

View Article and Find Full Text PDF

Aim: To investigate the association between the programmed death-1(PD-1) polymorphisms and genetic susceptibility of chronic hepatitis B virus (HBV) infection in Chinese patients.

Methods: Two single nucleotide polymorphisms (SNPs), PD-1.1 G > A and PD-1.

View Article and Find Full Text PDF

Objective: To evaluate the surgical technique of "Kou mode of hepatic hilar anastomosis" in the treatment for type III or IV hilar cholangiocarcinoma.

Methods: The clinical data of 89 patients with type III or IV hilar cholangiocarcinoma surgically treated in our department between Jan. 1990 and Jan.

View Article and Find Full Text PDF

Background: Estrogen receptor alpha (ER alpha) is the most important endocrine therapy responsiveness predictor for women with breast cancer. The accuracy of the prediction of the response to endocrine therapy was thought to be affected by involving the estrogen receptor coregulatory proteins and cross-talk between ER and other growth factor-signaling networks. Nuclear corepressor 1 (NCOR1) is one of the ER a transcription repressor.

View Article and Find Full Text PDF

Objective: To investigate the effect of high-volume continuous hemofiltration on inflammatory reaction in experimental severe acute pancreatitis (SAP) in pigs.

Methods: SAP was reproduced in pigs by intraductal injection of sodium taurocholate and trypsin, and they were randomly divided into three groups. Control group consisted of animals with SAP running its spontaneous course.

View Article and Find Full Text PDF

Aim: To investigate the potential role of continuous venovenous hemofiltration (CVVH) in hemodynamics and oxygen metabolism in pigs with severe acute pancreatitis (SAP).

Methods: SAP model was produced by intraductal injection of sodium taurocholate (4%, 1 mL/kg body weight (BW)) and trypsin (2 U/kg BW). Animals were allocated either to untreated controls as group 1 or to one of two treatment groups as group 2 receiving a low-volume CVVH (20 mL/(kg.

View Article and Find Full Text PDF

Objective: To observe the changes in hemodynamics and oxygen metabolism in pigs with severe acute pancreatitis (SAP) so as to provide a theoretical basis for clinical treatment.

Methods: A porcine model of SAP was reproduced by infusing normal saline (1 ml/kg) of sodium taurocholate (4%) and trypsin (1%) into the pancreatic duct (n=8). Heart rate (HR), central venous pressure (CVP), mean arterial pressure (MAP), pulmonary arterial wedge pressure (PAWP), mean pulmonary arterial pressure(MPAP) and cardiac output were continuously measured with the aid of Swan-Ganz catheter and electrocardiography monitor, and cardiac index (CI) was calculated.

View Article and Find Full Text PDF