Circular RNA hsa_circ_0000700 promotes cell proliferation and migration in Esophageal Squamous Cell Carcinoma by sponging miR-1229.

Accumulating evidence has demonstrated that circular RNAs (circRNAs) are involved in the pathogenesis of cancer, including that of esophageal squamous cell carcinoma (ESCC). The current study aimed to investigate the role of hsa_circ_0000700 in ESCC. hsa_circ_0000700, miR-1229, and related functional gene expression was measured by RT-qPCR.

DCE-MRI-Derived Volume Transfer Constant (K) and DWI Apparent Diffusion Coefficient as Predictive Markers of Short- and Long-Term Efficacy of Chemoradiotherapy in Patients With Esophageal Cancer.

This study aimed to evaluate both the short- and long-term efficacies of chemoradiotherapy in relation to the treatment of esophageal cancer . This was achieved through the use of dynamic contrast-enhanced magnetic resonance imaging-derived volume transfer constant and diffusion weighted imaging-derived apparent diffusion coefficient . Patients with esophageal cancer were assigned into the sensitive and resistant groups based on respective efficacies in chemoradiotherapy.

Effect of number and ratio of positive lymph nodes in hypopharyngeal cancer.

Background: The number and ratio of positive lymph nodes are important prognostic factors in gastric cancer, but there is little data reported in hypopharyngeal cancer.

Methods: Medical data from 81 patients with hypopharyngeal cancer undergoing radical hypopharyngectomy and cervical lymph node dissection were reviewed.

Results: The median survival time was 84, 54, 30, and 13 months in patients with N0, N1, N2, and N3, respectively, and 84, 51, and 17 months with positive lymph node ratios (N ratio) 0, <10%, and >10%, respectively.

[Clinicopathological and prognostic analysis of 178 patients with hypopharyngeal cancer].

Objective: To study the clinicopathological characteristics and the prognostic factors in patients with hypopharyngeal cancer.

Methods: Clinical and pathological data of 178 cases with hypopharyngeal cancer from January 2000 to December 2006 were studied.

Results: Of the 178 hypopharyngeal cancer, the median survival time was 42.

[Concurrent chemoradiotherapy followed by adjuvant chemotherapy for stage III-IVa nasopharyngeal carcinoma].

Background & Objective: Most studies on chemoradiotherapy for advanced nasopharyngeal carcinoma (NPC) showed that induction chemotherapy before radiotherapy could not improve the survival of the patients, but the effect of adjuvant chemotherapy after radiotherapy on advanced NPC is uncertain. A study showed that concurrent chemoradiotherapy could improve the prognosis of advanced NPC. This study was to evaluate the efficacy of concurrent chemoradiotherapy followed by adjuvant chemotherapy on stage III-IVa nasopharyngeal carcinoma (NPC).

[Dosimetry of translating scanning beam irradiation].

Background & Objectives: It was difficult to get a good tissue dose distribution using fixed field irradiation technique in large field. But the translating scanning beam irradiation can make it. This study was designed to create a treatment method and to evaluate the dosimetry of translating scanning beam irradiation and the clinical indications.