Publications by authors named "Zhen-Dan Zhao"
Gelatin/polycaprolactone membranes promote endometrial regeneration and restore fertility.
Gynecol Endocrinol
December 2024
Objective: To investigate the effectiveness of gelatin/polycaprolactone (GT/PCL) membranes for restoring endometrial structure and function and fertility in a rat model of endometrial injury.
Methods: We randomized 125 female Sprague-Dawley (SD) rats to the sham, natural repair (NR), estrogen (E), GT/PCL, and E-GT/PCL groups. Except for the sham group, all rats underwent uterine curettage.
Purpose: Hashimoto's thyroiditis (HT) is one of the most commonly encountered types of autoimmune thyroid disorders (AITDs), influenced by environmental factors, genetics, and the immune system. Previous research has shown a correlation between gut microbiota and HT, as well as the involvement of immune cells in its onset and progression. We aimed to investigate whether immune cells act as intermediaries in the causal relationship between gut microbiota and HT.
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- Breast cancer (BC) is a complex cancer with a poor prognosis, and a new type of cell death called disulfidptosis is linked to its development, especially under glucose deficiency.
- Researchers identified important genes related to glucose metabolism in cancer and used machine learning to create a prognostic model with these genes, which could classify BC patients into high-risk and low-risk groups.
- The model showed promise for predicting BC patient outcomes and treatment responses, with low-risk patients generally responding better to immunotherapy and chemotherapy.