Publications by authors named "Zhen-Bo Huang"
Scandium (Sc) is the lightest non-main-group element and transforms to a host-guest (H-G) incommensurate structure under gigapascal (GPa) pressures. While the host structure is stable over a wide pressure range, the guest structure may exist in multiple forms, featuring different incommensurate ratios, and mixing up to generate long-range "disordered" guest structures. Here, we employed the recently developed global neural network (g-NN) potential and the stochastic surface walking (SSW) global optimization algorithm to explore the global potential energy surface of Sc under various pressures.
View Article and Find Full Text PDFThe function of the brainstem Hap1-Ahi1 complex in the regulation of feeding behavior was investigated. When mice were fasted or treated with 2-deoxy-D-glucose (2-DG), Hap1-Ahi1 was significantly upregulated. By using streptozotocin (STZ) to decrease the circulating insulin in mice, Hap1-Ahi1 was significantly increased.
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- * While it is generally associated with negative effects on learning and memory, some studies suggest it might have no impact or even positive effects in certain contexts.
- * The review examines both the adverse and potentially beneficial effects of IL-1β on cognition and highlights key factors that could influence these outcomes.
Article Synopsis
- - The study investigated how lipopolysaccharide (LPS) affects memory retrieval, specifically looking at the interaction between the immune system and memory processes in mice.
- - Mice were trained using the Morris water maze, and after LPS administration, their spatial memory retrieval was assessed; IL-1β levels in the hippocampus were also measured.
- - The results showed that while LPS caused sickness behavior and increased IL-1β levels, it did not significantly impact the mice's ability to recall spatial memories during the testing phase.
Article Synopsis
- * Mice injected with scopolamine (a muscarinic antagonist) before a spatial memory test relied on the water maze showed impaired retrieval, indicating cholinergic involvement in this process.
- * However, scopolamine did not affect the retrieval of fear memory in the inhibitory avoidance task, suggesting that the cholinergic system is not critical for retrieving fear-related information.