Publications by authors named "Zhen Xing Ren"
Diabetic cardiomyopathy (DCM) is a cardiovascular disease which has been reported as a major cause of mortality worldwide for several years. Berberine (BBR) is a natural compound extracted from a Chinese herb, with a clinically reported anti‑DCM effect; however, its molecular mechanisms have not yet been fully elucidated. The present study indicated that BBR markedly alleviated DCM by inhibiting IL‑1β secretion and the expression of gasdermin D (Gsdmd) at the post‑transcriptional level.
View Article and Find Full Text PDFArticle Synopsis
- A new cage-type calix[4]pyrrole has been developed that includes a pyridinebisthiazolamine group for enhanced function.
- In its protonated state, this receptor exhibits a strong preference for sulfate ions compared to various other inorganic anions.
- The receptor can effectively extract sulfate ions from a heavily concentrated aqueous solution, demonstrating a recyclable method for liquid-liquid extraction involving H/SO to CHCl.
Article Synopsis
- A new artificial anion binding receptor has been created using calix[4]pyrrole and benzenebistriazole.
- This receptor has a strong and selective affinity for binding sulfate ions when in water.
- In its solid form, the receptor interacts with sulfate ions using a 3D cavity, forming multiple hydrogen bonds.
Article Synopsis
- A photonic spiking neural network (SNN) using excitable vertical-cavity surface-emitting lasers with a saturable absorber is proposed to replicate sound direction detection in the brain for the first time.
- The timing differences of spikes between two neurons indicate the direction of sound, and the study identifies the optimal weight matrix for accurate sound location detection.
- The system shows a much higher resolution at the nanosecond scale compared to biological systems and presents lower energy consumption, highlighting its potential for advanced photonic neuromorphic computing.
Hepatic fibrosis is the main pathological basis for chronic cirrhosis, and activated hepatic stellate cells (HSCs) are the primary cells involved in liver fibrosis. Our study analyzed anti-fibrosis long noncoding RNAs (lncRNAs) in activated human HSCs (hHSCs). We performed RNA sequencing (RNA-seq) and bioinformatics analysis to determine whether lncRNA expression profile changes between hHSCs activation and quiescence.
View Article and Find Full Text PDFRhodiola spp. are rare and endangered alpine plants widely used as medicines and food additives by many civilizations since ancient times. Their main effective ingredients (such as salidroside and p-tyrosol) are praised to exhibit pharmacologic effects on high-altitude sickness and possess anti-aging and other adaptogenic capacities based on their antioxidant properties.
View Article and Find Full Text PDF