The potential role of secondary metabolites in modulating the flavor and taste of the meat.

Flavor is one of the most significant characteristics of beef palatability and it can eventually affect the consumer's acceptance of a beef product and purchasing habits. Variation in beef quality is large and is due to many factors, such as differences in genetic background, sex, age, management and nutrition. The consumer's decision to purchase beef is guided by the perception of healthiness and a variety of sensory traits including color, tenderness, juiciness, and aroma or flavor.

Enhanced Yellow Persistent Luminescence in SrSiO:Eu through Ge Incorporation.

The SrSiO:Eu phosphor has attracted considerable attention for applications in white LEDs owing to its highly efficient yellow emission under violet-blue excitation. We report herein an enhancement of yellow persistent luminescence in SrSiO:Eu through Ge incorporation. The strongest persistent luminescence intensity is observed for Sr(SiGe )O:Eu with x = 0.

Insights into functional microbial succession during nitrogen transformation in an ectopic fermentation system.

The ectopic fermentation system (EFS) is an advanced technology for treating farm wastewater, and it reduces ammonia nitrogen emission and nitrogen loss of fermentation products. This study observed the functional bacteria succession related to nitrogen metabolism in EFS by high throughput sequencing, and evaluated their associations with environmental factors. Results revealed that with the changes of temperature, pH, moisture content, and nitrogen content during fermentation, the species richness and diversity of ammonia oxidizing bacteria (AOB) with amoA increased, but those of denitrifying bacteria carrying nirK and nosZ decreased.

Functional study of Csrbohs in defence response against Xanthomonas citri ssp. citri.

NADPH oxidases, encoded by rbohs (respiratory burst oxidase homologues), transfer electrons from NADPH to molecular oxygen (O2) to generate superoxide anion (O2•-), which is the first step in the formation of hydrogen peroxide (H2O2) in the plant-pathogen interaction system. In the present work, six citrus rbohs (Csrbohs) genes were identified in citrus, and their possible involvement in resistance to Xanthomonas citri ssp. citri (Xcc) was examined.

Genetic substructure and forensic characteristics of Chinese Hui populations using 157 Y-SNPs and 27 Y-STRs.

The Hui group is the second largest ethnic minority and one of the most widespread ethnic groups in China. However, the genetic architecture of the Hui population remains largely unexplored, particularly with respect to the male-specific region of the Y chromosome. Here, we studied nine Hui populations (Xinjiang, Qinghai, Gansu, Ningxia, Shaanxi, Henan, Shandong, Sichuan, Yunnan) using 157 Y-chromosome single nucleotide polymorphisms (Y-SNPs) and 27 short tandem repeats (Y-STRs) to unravel their genetic substructure and forensic characteristics.

The management and composition of symptomatic seminal vesicle calculi: aetiological analysis and current research.

Objective: To report our experience in the diagnosis, minimally invasive treatment, and composition of seminal vesicle calculi (SVC).

Patients And Methods: In the present study, we evaluated 20 patients who were admitted to our hospital from January 2013 to January 2018. All the patients were diagnosed with intractable haematospermia and SVC.

Evaluation of ecosystem service value of the grape industry at the eastern foot of Helan Mountain, Ningxia, China.

Using statistical data from Statistics Bureau of Ningxia Hui Autonomous Region, the Grape Industry Development Bureau of Ningxia Hui Autonomous Region, and National Bureau of Statistics, ecosystem service value of grape industry at the eastern foot of Helan Mountain in Ningxia was evaluated from eight facets, i.e., food production, carbon fixation and oxygen release, air purification, soil conservation, water-holding, water conservation and efficiency, eco-tourism, and ecological poverty alleviation.

Low fouling electrochemical sensing in complex biological media by using the ionic liquid-doped conducting polymer PEDOT: application to voltammetric determination of dopamine.

An electrochemical sensor that can resist biofouling even when operated in complex biological medium is developed for the determination of dopamine. It is based on the use of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) that is doped with the water insoluble ionic liquid (IL), 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide. A glassy carbon electrode modified with PEDOT/IL is shown to enable accurate determination of dopamine, as a model analyte in the presence of high concentrations of proteins, and resist biological fouling even in native serum.

Epitope-loaded nanoemulsion delivery system with ability of extending antigen release elicits potent Th1 response for intranasal vaccine against Helicobacter pylori.

Background: Helicobacter pylori (H. pylori) infection remains a global public health issue, especially in Asia. Due to the emergence of antibiotic-resistant strains and the complexity of H.

Effect of polyhedron deformation on the 5d energy level of Ce in lanthanide aluminum perovskites.

The crystal-field levels of Ce3+ in a series of lanthanide aluminum perovskites have been investigated with reference to polyhedron deformation. For each compound, the corresponding ideal cuboctahedron is derived through a least-square procedure. The virtual energy levels of Ce3+ in these ideal polyhedrons are then obtained considering both crystal-field splitting and spin-orbit coupling.

Enhanced Persistence Properties through Modifying the Trap Depth and Density in YAlGaO:Ce,Yb Phosphor by Co-doping B.

Long persistence phosphors with high emitting intensity are promising materials for safety signage and energy storage applications. Herein, an improved persistent luminescence of YAlGaO phosphor by co-doping Ce, Yb, and B is achieved using conventional solid-state reaction. On one hand, the incorporation of HBO can improve the crystallinity; on the other hand, B can replace Al/Ga in tetrahedral sites in the host lattice, causing lattice contraction and modifying the trap depth and density.

Determinants of early afterdepolarization properties in ventricular myocyte models.

Early afterdepolarizations (EADs) are spontaneous depolarizations during the repolarization phase of an action potential in cardiac myocytes. It is widely known that EADs are promoted by increasing inward currents and/or decreasing outward currents, a condition called reduced repolarization reserve. Recent studies based on bifurcation theories show that EADs are caused by a dual Hopf-homoclinic bifurcation, bringing in further mechanistic insights into the genesis and dynamics of EADs.

Study on the interaction between pyridoxal and CopC by multi-spectroscopy and docking methods.

The interaction between pyridoxal hydrochloride (HQ) and apoCopC was investigated using Fourier transform infrared spectroscopy (FTIR), isothermal titration calorimetry (ITC), circular dichroism (CD), fluorescence spectroscopy, three-dimensional (3D) fluorescence spectroscopy, fluorescence lifetime, TNS fluorescence and docking methods. FTIR, CD, TNS fluorescence and fluorescence lifetime experiments suggested that the apoCopC conformation was altered by HQ with an increase in the random coil content and a reduction in the β-sheet content. In addition, the data from fluorescence spectroscopy, 3D fluorescence spectroscopy and molecular docking revealed that the binding site of HQ was located in the hydrophobic area of apoCopC, and a redshift of the HQ fluorescence spectra was observed.

Development of a safety and efficacy nanoemulsion delivery system encapsulated gambogic acid for acute myeloid leukemia in vitro and in vivo.

This study aimed to improve the solubility, reduce the side effects and enhance the efficacy of gambogic acid against acute myeloid leukemia in vitro and in vivo. This oil-in-water nanoemulsion (average size 17.20 ± 0.

Biodegradable nanoprobe based on MnO nanoflowers and graphene quantum dots for near infrared fluorescence imaging of glutathione in living cells.

Near infrared (NIR) emitting semiconductor quantum dots can be excellent fluorescent nanoprobes, but the poor biodegradability and potential toxicity limits their application. The authors describe a fluorescent system composed of graphene quantum dots (GQDs) as NIR emitters, and novel MnO nanoflowers as the fluorescence quenchers. The system is shown to be an activatable and biodegradable fluorescent nanoprobe for the "turn-on" detection of intracellular glutathione (GSH).

The immunophenotypic characteristics and flow cytometric scoring system of acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1.

Introduction: The translocation t(8;21) is one of the most frequent chromosome translocations in AML. Molecular (cyto)genetics is regarded as the gold standard for diagnosis. However, due to the complicated variety of AML-related genetic abnormalities, comprehensive screening for all of these abnormalities may not be cost-effective.

Charge Transfer, Local Structure, and the Inductive Effect in Rare-Earth-Doped Inorganic Solids.

The charge transfer (CT) process is widely present in inorganic compounds. However, the explanation of this process accounting the inductive effect was not reported. In this work, through the analysis of local structure about the second nearest cations (SNCs) in some compounds doped with trivalent lanthanide, we verify successfully the important role of the inductive effect in the CT process.

Universal Design of Selectivity-Enhanced Photoelectrochemical Enzyme Sensor: Integrating Photoanode with Biocathode.

Previous work on photoelectrochemical (PEC) biosensors has demonstrated that the photoanode-based type possesses satisfying sensitivity, because photoanode utilize electrons as the majority charge carriers and a distinct photocurrent can be generated when electron donors are furnished. However, as hole-oxidation reaction occurs at the photoanode interface, the photoanode-based PEC sensor has inferior anti-interference capacity to reductive substances coexisting in the biological sample, leading to a challenged selectivity. Herein, a universal design on selectivity-enhanced PEC enzyme sensor was proposed by integrating a photoanode with a biocathode.

An immunopotentiator, ophiopogonin D, encapsulated in a nanoemulsion as a robust adjuvant to improve vaccine efficacy.

Unlabelled: As an ingredient of vaccines, adjuvants are indispensable for enhancing and directly inducing robust and extensive adaptive immune responses associated with vaccine antigens. In this study, we initially determined that a new molecular immunopotentiator, ophiopogonin D (OP-D), enhanced the antibody response to antigen. Because OP-D has certain disadvantages, including poor solubility, we next encapsulated OP-D in a nanoemulsion adjuvant (nanoemulsion-encapsulated OP-D, NOD) using low-energy emulsification methods.

Synthesis of amphiphilic graphitic silver nanoparticles with inherent internal standards: an efficient strategy for reliable quantitative SERS analysis in common fluids.

An efficient strategy for reliable quantitative SERS analysis in common fluids was proposed by amphiphilic functionalization of graphitic silver nanoparticles with inherent internal standards by azides, and has the merits of high accuracy, enhanced dispersity and outstanding stability in fluids.

A Quantitative Dot Blot Assay for AAV Titration and Its Use for Functional Assessment of the Adeno-associated Virus Assembly-activating Proteins.

While adeno-associated virus (AAV) is widely accepted as an attractive vector for gene therapy, it also serves as a model virus for understanding virus biology. In the latter respect, the recent discovery of a non-structural AAV protein, termed assembly-activating protein (AAP), has shed new light on the processes involved in assembly of the viral capsid VP proteins into a capsid. Although many AAV serotypes require AAP for assembly, we have recently reported that AAV4, 5, and 11 are exceptions to this rule.

[Effects of invasive Cenchrus spinifex on nitrogen pools in sandy grassland].

Cenchrus spinifex is an invasive plant found in large areas of northern China. In this study, we focused on analysis of the effects of C. spinifex on soil nitrogen and plant nitrogen pools in Horqin sandy grassland.

Development of Infectious cDNA Clones of Citrus Yellow Vein Clearing Virus Using a Novel and Rapid Strategy.

Yellow vein clearing disease (YVCD) causes significant economic losses in lemon and other species of citrus. Usually, citrus yellow vein clearing virus (CYVCV) is considered to be the causal agent of YVCD. However, mixed infection of CYVCV and Indian citrus ringspot virus (ICRSV) or other pathogens is often detected in citrus plants with YVCD.

Method Using Water-Based Solvent to Prepare LiLaZrO Solid Electrolytes.

Li-garnet LiLaZrO (LLZO) is a promising candidate of solid electrolytes for high-safety solid-state Li ion batteries. However, because of its high reactivity to water, the preparation of LLZO powders and ceramics is not easy for large-scale amounts. Herein, a method applying water-based solvent is proposed to demonstrate a possible solution.