Line integral compressed ultrafast photography for large time-scale measurements.

Compressed ultrafast photography (CUP) has attracted significant attention in the field of ultrafast optical imaging but is inherently constrained by a trade-off between sequence depth and spatial resolution. To address this limitation, we present a novel, to the best of our knowledge, system called spatial line integral CUP (LI-CUP). LI-CUP utilizes a cylindrical lens to compress each encoded time-slice frame into a spatial line, which is then recorded by a streak camera with a narrow slit.

Prognostic model for log odds of negative lymph node in locally advanced rectal cancer via interpretable machine learning.

No studies have examined the prognostic value of the log odds of negative lymph nodes/T stage (LONT) in locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT). We aimed to assess the prognostic value of LONT and develop a machine learning model to predict overall survival (OS) and disease-free survival (DFS) in LARC patients treated with nCRT. The study included 820 LARC patients who received nCRT between September 2010 and October 2017.

sp. nov., a novel ascomycetous yeast species from Xinghuacun Fenjiu old workshop, Shanxi province of China.

Four yeast strains belonging to the ascomycetous yeast genus were isolated from the mixture of remnants of steamed sorghum, Daqu powder and the fermented grain that fell off during transportation on the ground in the workshop which were collected in Xinghuacun Fenjiu old workshop, Shanxi province, PR China. We propose the name sp. nov.

Investigation of the Microstructures and Mechanical Properties of Sn-Cu-Bi-In-Ni Solders.

The development of Ag-free Sn solders has attracted significant attention due to the requirement of high-density electronic packaging. In this study, we investigate the Ni element on the microstructures and mechanical properties of Ag-free Sn-Cu-Bi-In solders. This paper details the microstructures and phases of the as-prepared Sn-Cu-Bi-In-Ni solders, as well as its mechanical properties.

Exploring Inflammatory Changes in the Peripheral Blood of Type 2 Diabetes Mellitus in China.

Objective: Type 2 diabetes mellitus (T2DM) is a serious, chronic metabolic disease globally and its pathogenesis is not completely understood yet. This study aimed to thoroughly investigate the fluctuation of inflammatory markers in the peripheral blood of patients with T2DM, which are rarely reported.

Methods: Peripheral blood samples from patients with T2DM and healthy individuals, as well as their clinical information, were collected at the Second Affiliated Hospital of Soochow University.

Chemiluminescent Probe for Enhanced Visualization of Renal Ischemia-Reperfusion Injury via Pyroglutamate Aminopeptidase-1 Activation.

The absence of an effective imaging tool for diagnosing renal ischemia-reperfusion injury (RIRI) severely delays its treatment, and currently, no definitive clinical interventions are available. Pyroglutamate aminopeptidase-1 (PGP-1), a potential inflammatory cytokine, has shown considerable potential as a biomarker for tracing the inflammatory process in vivo. However, its exact role in the enhanced visualization of RIRI in complex biological systems has yet to be fully established.

Microstructural and mechanical responses of Sn58Bi/Cu composite solder joints with 0.1wt.% Ni and carbon fiber addition.

The effect of carbon fibers (Cf) and Ni nanoparticles addition on the melting point, microstructure, shear strength, indentation hardness and indentation creep of SnBi/Cu solder joints were explored. Composite solder with various Cf percentages (0, 0.02, 0.

Identification of the saccharifying microbiota based on the absolute quantitative analysis in the batch solid-state fermentation system.

The fermentation process of Chinese baijiu, a distinctive example of batch solid-state fermentation (BSSF), involves the recurrent use of the same raw material to optimize starch utilization. However, it is unclear which microorganisms are able to metabolize low concentration starch effectively. In this study, we successfully identified the key saccharifying microbiota that degraded low-concentration starch in the BSSF system by absolute quantification techniques.

Extraction of short-chain fatty acid ethyl Ester in Baijiu using covalent organic framework-based magnetic nanoparticles: Theoretical screening and experimental validation.

Short-chain fatty acid ethyl esters (SFAEEs) are critical aroma compounds in Baijiu, and their wider concentration range can lead to differences in the quality grade of Baijiu. Efficiently designing an SFAEEs adsorbent before instrument analysis remains challenging. In this work, nine functionalized covalent organic frameworks (COFs) with different postmodification groups were designed for targeting SFAEEs.

3D printed-TCP scaffolds loaded with SVVYGLR peptide for promoting revascularization and osteoinduction.

It is crucial for the successful transplantation of large segmental bone defects to achieve rapid vascularization within bone scaffolds. However, there are certain limitations including uncontrolled angiogenesis and inadequate vascular function. Therefore, there is an urgent need to develop bone scaffolds with functional vascular networks.

Prognostic value of preoperative D-dimer to albumin ratio in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy.

Background: The prognostic value of Albumin and D-dimer has been established for multiple tumor types, indicating their potential for predicting tumor development. Nevertheless, the predictive capability of the DDI-to-albumin ratio (DAR) in locally advanced rectal cancer (LARC) remains uncertain.

Purpose: The objective of this study was to investigate the prognostic significance of the DAR in LARC.

Advancing pathogen and tumor copy number variation detection through simultaneous metagenomic next-generation sequencing: A comprehensive review.

In clinical practice, timely and accurate diagnosis can effectively reduce unnecessary treatment, avoid high medical costs, and prevent adverse prognoses. However, some patients with malignant tumors and those with infection often exhibit similar symptoms, which are difficult to distinguish, posing challenges in accurate clinical diagnosis. Metagenomic next-generation sequencing (mNGS) technology has been widely applied to confirm the source of infection.

Integrated analysis of clinical indicators and mechanical properties in cancellous bone.

Cancellous bone plays a critical role as a shock absorber in the human skeletal system. Accurate assessment of its microstructure and mechanical properties is crucial for osteoporosis diagnosis and treatment. However, various methods with different indicators are adopted currently in the clinical and laboratory assessments which lead to confusion and inconvenience for cancellous bone analysis.

Draw-tower-grating-based Fabry-Perot interferometers for simultaneous measurements of temperature and salinity.

In this paper, a fiber optic sensor with draw-tower-grating (DTG)-based Fabry-Perot interferometers (FPIs) are proposed to measure the temperature and salinity of seawater simultaneously. The sensing structure utilizes DTG as the reflector, and two adjacent gratings can be cascaded to compose an FPI. By employing moisture-sensitive materials to the surface of the optical fiber, the variation in salinity can be measured by the axial strain applied by the coating on the sensing optical fiber.

Efficient methane fermentation from the waste of a novel straw alkali-heat pretreatment-butyric acid fermentation process.

The butyric acid biorefinery technology for straw is highly significant for environmental protection and the restructuring of the energy system. However, this process produces waste from alkali-heat pretreatment (PW) and butyric acid fermentation (FW). In this study, the feasibility of methane fermentation from the wastes was confirmed, with the methane production from PW and FW of 351.

Three-dimensional gas-foamed scaffolds decorated with metal phenolic networks for cartilage regeneration.

Inflammation is a major impediment to the healing of cartilage injuries, yet bioactive scaffolds suitable for cartilage repair in inflammatory environments are extremely rare. Herein, we utilized electrospinning to fabricate a two-dimensional nanofiber scaffold (2DS), which was then subjected to gas foaming to obtain a three-dimensional scaffold (3DS). 3DS was modified with metal phenolic networks (MPNs) composed of epigallocatechin gallate (EGCG) and strontium ions (Sr) to afford a MPNs-modified 3D scaffold (3DS-E).

Inhibition of inflammatory osteoclasts accelerates callus remodeling in osteoporotic fractures by enhancing CGRPTrkA signaling.

Impaired callus remodeling significantly contributes to the delayed healing of osteoporotic fractures; however, the underlying mechanisms remain unclear. Sensory neuronal signaling plays a crucial role in bone repair. In this study, we aimed to investigate the pathological mechanisms hindering bone remodeling in osteoporotic fractures, particularly focusing on the role of sensory neuronal signaling.

Discrete Illumination-Based Compressed Ultrafast Photography for High-Fidelity Dynamic Imaging.

Compressed ultrafast photography (CUP) can capture irreversible or difficult-to-repeat dynamic scenes at the imaging speed of more than one billion frames per second, which is obtained by compressive sensing-based image reconstruction from a compressed 2D image through the discretization of detector pixels. However, an excessively high data compression ratio in CUP severely degrades the image reconstruction quality, thereby restricting its ability to observe ultrafast dynamic scenes with complex spatial structures. To address this issue, a discrete illumination-based CUP (DI-CUP) with high fidelity is reported.