Publications by authors named "Zhen Ning"

As the largest hydropower project in the world, the Three Gorges Reservoir (TGR) exerts significant backwater effects, leading to various water quality issues. The Xiangxi River, the largest tributary near the dam, has experienced algal bloom phenomena for several years. However, the characteristics and influencing factors of water quality during different operational periods of the reservoir remain unclear.

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  • Recent studies focus on creating hybrid systems of magnets and superconductors that exhibit topological superconductivity.
  • The research demonstrates that using Floquet engineering with antiferromagnetic layers and s-wave superconductors can induce chiral topological superconductivity through light interaction that disrupts time-reversal symmetry.
  • The ability to control these topological phases with elliptically polarized light offers a novel way to manipulate superconducting properties through related changes in valley pairs, making this approach promising for experimental exploration.
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To explore differences among the elderly people (aged over 50 years old) living with HIV (PLWH) who are receiving antiretroviral therapy (ART), we collected and analyzed data using cross-sectional research methods. Among 520 elderly PLWH on ART, those over 60 years old, compared to those aged 50-60, had lower levels of education, more retirees in occupation distribution, a lower rate of active consultation, a higher proportion of heterosexual transmission, and more complications. Additionally, this study demonstrated a greater incidence of severe disease symptoms and a higher rate of ART failure.

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Phase change materials (PCMs) offer promising solutions for efficient thermal management in electronic devices, energy storage systems, and renewable energy applications due to their capacity to store and release significant thermal energy during phase transitions. This study investigates the thermal and physical properties of Bi-In-Sn/WO composites, specifically for their use as phase change thermal interface materials (PCM-TIMs). The Bi-In-Sn/WO composite was synthesized through mechanochemical grinding, which enabled the uniform dispersion of WO particles within the Bi-In-Sn alloy matrix.

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The HIV/AIDS epidemic has changed significantly over the past 40 years. Changes in AIDS intervention strategies over time and across regions may have influenced epidemiological characteristics and intervention strategies. The aim of the current study was to analyze the changes in multi-year epidemiological characteristics of newly reported HIV/AIDS cases in an urban area (the Fengxian District of Shanghai) from 2001 to 2019 based on the national AIDS comprehensive data information system and Shanghai Statistical Yearbook.

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Men who have sex with men (MSM) bear a disproportionate burden of HIV in China and are particularly vulnerable to mental health challenges. This study is phase one of a multi-phase project that aimed to identify unmet needs of MSM living with HIV to inform the development of a multi-level intervention. We interviewed 24 stakeholders through videoconferencing, including 15 MSM living with HIV, five staff from a community-based organization serving gender and sexual minority individuals, and four staff from the Centers for Disease Control and Prevention in Shanghai, China.

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What Is Already Known About This Topic?: The World Health Organization (WHO) has recommended the inclusion of the C-reactive protein (CRP) test in active tuberculosis (ATB) screening algorithms among human immunodeficiency virus (HIV)-infected individuals. The performance of the CRP test in African regions has been well-documented.

What Is Added By This Report?: This study analyzed data from a big data platform of Shanghai medical records together with infectious disease surveillance systems.

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  • The study examined drug resistance in HIV among newly diagnosed individuals in China from 2018 to 2023 to adapt treatment guidelines.
  • Out of over 22,000 individuals, 4.36% had at least one transmitted drug resistance (TDR) mutation, with the most common being linked to nonnucleoside reverse transcriptase inhibitors.
  • The prevalence of TDR mutations notably increased from 4.05% to 5.39% over the study years, supporting the ongoing use of NNRTI-based treatment regimens for HIV.
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  • China adopted the WHO's "treat all" policy in 2016, aiming to improve HIV care through the 95-95-95 targets, which include diagnosing 95% of HIV positive individuals, getting 95% of those diagnosed on treatment, and achieving viral suppression in 95% of treated individuals.
  • Data from 2004 to 2023 showed significant advancements in these targets, correlating with a drop in new HIV infections, as evidenced by a dip in clustering frequency and a peak in cases documented in 2014.
  • The study concludes that while progress has been made, China needs to focus on increasing efforts in the first "95" target to further reduce HIV transmission rates and improve overall outcomes.
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A novel technique was proposed for processing silkworm pupae by combining plasma- activated water (PAW) with ultrasound (US). The microbial diversity and quality characteristics of the silkworm pupae were also evaluated. The results of the microbial diversity analysis indicated that PAW combined with US treatment significantly reduced the relative abundance of Streptococcaceae, Leuconostocaceae, and Acetobacteraceae from 32%, 18% and 16% to 27%, 11% and 11%, respectively.

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Drug-resistant poses an urgent threat to public health. Recently, sitafloxacin, a new-generation fluoroquinolone, has shown high in vitro activity against drug-resistant . However, data on its effectiveness in clinical isolates remains limited.

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Amivantamab is the first dual-specificity antibody targeting EGFR and MET, which is approved for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations. Cardiovascular toxicities related to amivantamab have not been reported in the CHRYSALIS study. However, the occurrence of cardiovascular events in the real world is unknown.

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Background: With the continuous development and progress of medical technology, the position of surgical nursing in the field of clinical medicine is becoming increasingly prominent. As an important branch of the surgical field, the nursing requirements and difficulty of gastrointestinal surgery are also increasing. In order to improve the teaching quality of nursing care in gastrointestinal surgery, many educators and researchers are actively exploring new teaching methods.

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Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and may occur with lymph node and/or extranodal involvement. However, DLBCL with intracardiac mass is exceedingly rare. In the reported literature, the intracardiac infiltration of DLBCL mostly involves the right ventricle.

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Purpose: Given the limited research on health care utilization among transgender women in China, we described the use of primary health care and gender-affirming health care, and the associations between utilization of gender-affirming health care and depression and sexual risk behaviors.

Methods: We conducted a cross-sectional survey in 2017 among a purposive sample of transgender women in Shanghai, China (=199). We examined correlates of health care utilization and its association with depression and sexual risk behaviors with Chi-square (), Fisher's exact tests, and analysis of variance.

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Background/objective: People living with HIV (PLWH) are prone to mental health problems and evidence indicates that HIV-related stigma can negatively impact mental health-related quality of life. This study explored potential mechanisms between HIV-related stigma and mental health-related quality of life, specifically whether anxiety or depression mediates, and whether social support moderates, the relationship.

Method: A total of 1197 Chinese PLWH participated in the study.

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Background: Mental health problems are common among men who have sex with men (MSM) living with HIV and may negatively affect medication adherence. Psychosocial interventions designed to address these urgent needs are scarce in China. Incorporating behavioral health theories into intervention development strengthens the effectiveness of these interventions.

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  • The study aimed to explore the protective effects of Zhenlong Xingnao capsules against cerebral ischemia-reperfusion injury (CIRI) and their mechanism through the Notch/NF-κB signaling pathway.
  • The research involved a rat model of middle cerebral artery occlusion (MCAO) where various treatment groups were assessed for improvements in learning, memory, and brain health indicators, alongside inflammation and oxidative stress assessment.
  • Results indicated that Zhenlong Xingnao capsules significantly enhanced neurological function and reduced harmful protein expressions, suggesting they may aid in neuron recovery post-ischemia, though efficacy was diminished with Jagged1 treatment.
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  • The study explored factors influencing nursing interns' attitudes about death at Jiangxi University of Technology between January and March 2021.
  • Data was collected from 210 nursing interns using a general information questionnaire and the Chinese version of the Death Attitude Depiction Scale, revealing a total score indicating a generally positive attitude, but with notable fear of death.
  • Factors such as religious belief, experiences with patient death during internships, reading related literature, and family discussions about death were identified as significant influences on these attitudes, contributing to a predictive model for total death attitude scores.
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Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a poor prognosis. Reprogramming of amino acid metabolism is one of the characteristics of PDAC, in which arginine metabolism is significantly altered in PDAC cells and is involved in important signaling pathways. Current studies have identified arginine deprivation as a potential strategy for PDAC treatment.

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Objectives: This study sought to identify potential change patterns and predictors of fasting plasma glucose (FPG) and lipid levels after initiating highly active antiretroviral therapy (HAART).

Methods: A retrospective cohort study was conducted on 1,572 patients tested positive for HIV who initiated HAART between January 2010 and October 2020 in Shanghai, China. The growth mixture models (GMM) were used for capturing subgroups of FPG trajectories as well as triglyceride (TG) and total cholesterol (TC) dual-trajectories.

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