Objective: A high sodium (HS) diet is believed to affect bone metabolism processes. Clarifying its impact on osseointegration of titanium (Ti) implants holds significant implications for postoperative dietary management of implanted patients.
Methods: This investigation probed the impact of sodium ions (Na ) on neovascularization and osteogenesis around Ti implants , utilizing micro-computed tomography, hematoxylin and eosin staining, and immunohistochemical analyses.