Publications by authors named "Zhen Li Qin"
Article Synopsis
- Long non-coding RNAs (lncRNAs) play important roles in cancer, with LOXL1-AS1 identified as a pro-oncogene in various tumors, particularly ovarian cancer.
- The study finds that LOXL1-AS1 is highly expressed in ovarian cancer tissue compared to adjacent non-cancerous tissue and interacts with miR-18b-5p and its target gene, VMA21.
- Results show that silencing LOXL1-AS1 or mimicking miR-18b-5p inhibits ovarian cancer cell growth and aggressiveness, indicating that LOXL1-AS1 promotes cancer cell proliferation and metastasis through a miR-18b-5p/VMA21 pathway.
Aims: This study aims to explore the independent predictors of gestational diabetes mellitus (GDM) in Chinese women with polycystic ovary syndrome (PCOS).
Methods: This cross-sectional study analyzed primigravid women with PCOS and classified them as those with and without GDM. Independent risk factors and model performance were analyzed using multivariate logistic regression and the area under the curve (AUC) of receiver operating characteristic (ROC), respectively.