Publications by authors named "Zhejun Dong"
Article Synopsis
- Androgens, essential sex hormones, are linked to health issues like cardiovascular diseases in conditions such as polycystic ovarian syndrome and may affect arterial stiffness through changes in the G protein-coupled estrogen receptor (GPER).
- The study evaluated the effects of the androgen dihydrotestosterone (DHT) and other hormones on the expression of GPER and estrogen receptor alpha (ERα) in vascular smooth muscle cells and in female mice over four weeks.
- Results indicated that DHT significantly decreased GPER levels while increasing body weight and more than doubling arterial stiffness in the treated mice compared to controls, highlighting the hormonal impact on cardiovascular health.
Three-dimensional (3D) concrete printing (3DCP) technology attracts significant attention from research and industry. Moreover, adequate mechanical performance is one of the primary properties for materials, meeting the demand of structural safety using 3DCP technology. However, research on curing conditions as the significant influence factor of mechanical capacity is required to accelerate the practical application of 3DCP technology.
View Article and Find Full Text PDFAconitase, the second enzyme of the tricarboxylic acid cycle encoded by ACO1 in the budding yeast Saccharomyces cerevisiae, catalyzes the conversion of citrate to isocitrate. aco1Δ results in mitochondrial DNA (mtDNA) instability. It has been proposed that Aco1 binds to mtDNA and mediates its maintenance.
View Article and Find Full Text PDF[Effects of fraction from Phyllanthus urinaria on thrombosis and coagulation system in animals].
Zhong Xi Yi Jie He Xue Bao
March 2004
Objective: To investigate the effects of PUW (a fraction containing 60% corilagin from a Chinese herbal plant Phyllanthus urinaria) on thrombosis and coagulation system.
Methods: Myers's method was used to evaluate the protection of intravenously administered PUW against the male mouse sudden death caused by injection of 75 mg/kg arachidonic acid in the tail vein; Charlton's method was modified to observe antithrombotic effect of PUW in rat electrically stimulated carotid artery thrombosis model; and the model of venous thrombosis was produced to investigate the antithrombotic effect of PUW. Rosette assay was used to observe the effect of PUW on platelet-neutrophil adhesion.