Publications by authors named "Zheer Kejlberg Al-Mashhadi"
Purpose: Osteoglycin is hypothesized to be metabolically active and may enhance insulin action. We hypothesized that osteoglycin levels increase during hyperglycemia as a physiological response to enhance the effects of insulin.
Methods: Eight healthy males were included in a cross-over study consisting of three study days following an 8 h fast.
Article Synopsis
- Type 2 diabetes (T2D) is linked to a higher risk of fractures, and this study investigates whether glucagon-like peptide 1 receptor agonists (GLP-1RA) affect fracture risk compared to dipeptidyl peptidase 4 inhibitors (DPP-4i) when used alongside metformin.
- The research conducted a cohort study with Danish health registries, focusing on patients treated with metformin and either GLP-1RA or DPP-4i between 2007 and 2018, employing statistical models to assess major osteoporotic fractures (MOF).
- Findings showed that patients on GLP-1RA exhibited a lower risk of MOF (haz
Background: Type 2 diabetes mellitus (T2D) is associated with an increased fracture risk. It is debated whether sodium-glucose cotransporter 2 (SGLT2) inhibitors influence fracture risk in T2D. We aimed to investigate the risk of major osteoporotic fractures (MOF) with SGLT2 inhibitors compared to glucagon-like peptide 1 (GLP-1) receptor agonists when used as add-on therapies to metformin.
View Article and Find Full Text PDF