[Observation of acupoint application of gel plaster on insomnia].

Objective: To observe the effect of acupoint application of gel plaster on quality of sleep and life in patients with insomnia.

Methods: A total of 63 patients with insomnia were randomized into a gel plaster group (32 cases, 1 case dropped off) and a placebo plaster group (31 cases). Acupoint application of gel plaster was applied at Yintang (GV 29) and Yongquan (KI 1) in the gel plaster group, placebo plaster was applied at the same acupoints in the placebo plaster group.

[Hereditary hemorrhagic telangiectasia caused by mutation in intron 4 of ALK1 gene: analysis of a HTT family].

Objective: To investigate the molecular pathogenesis of hereditary hemorrhagic telangiectasia (HHT).

Methods: Peripheral blood samples were collected from a HTT family, including the proband, female, aged 48, and her mother, elder brother, elder sister, younger brother, and son. HHT gene mutations were identified by PCR-SSCP and DNA sequencing and confirmed by reverse sequencing.