Publications by authors named "Zharkova L"
Article Synopsis
- The article discusses a multicenter study in Russia on infective endocarditis, focusing on the causes, antibiotic effectiveness, and drug usage patterns.
- The study analyzed 406 cases, finding that 35.5% had identifiable pathogens, primarily gram-positive cocci, with Staphylococcus aureus being the most common at 46.5%.
- The research highlighted the frequent use of aminoglycosides and third-generation cephalosporins in initial treatment, while adjustments in therapy often involved glycopeptides and fluoroquinolones.
Article Synopsis
- Russia started using a vaccine called PCV13 in 2014 to protect children from pneumonia!
- A study looked at healthy kids under 6 in different cities from 2016 to 2018, finding that most had not finished the full vaccine series!
- The results showed that vaccinated kids had fewer of the vaccine-targeted germs but more of other types compared to unvaccinated kids!
The effect of pulse-periodic microwave radiation (PPMR) of the pulse repetition frequency of 8-25 pulseper second, the peak power density of 1500 W/cm2 on the epididymal adipose tissue of micewas investigated. The effect was assessed by the changes in the fat mass and size of the irradiated adipocytes. It was found that the fat mass and size distribution of adipocytes are affected by irradiation.
View Article and Find Full Text PDFThe effect of repetitive pulsed X-ray (4 ns pulse duration, 300 kV accelerating voltage; 2.5 kA electron beam current) on the antioxidant enzyme activity in mouse liver mitochondria has been investigated. The mitochondrial suspension was exposed to single 4000 pulse X-ray radiation with repetition rates ranging between 10 and 22 pps (pulsed dose was 0.
View Article and Find Full Text PDFEffects of ionizing radiation registered in cells after low dose irradiation are still poorly understood. A pulsed mode of irradiation is even more problematic in terms of predicting the radiation-induced response in cells. Thus, the aim of this paper was to study and analyze the effects of dose and frequency of pulsed X-rays on the frequency of radiation-induced DNA double-strand breaks and their repair kinetics in human peripheral blood lymphocytes in vitro.
View Article and Find Full Text PDFArticle Synopsis
- The study assessed the effectiveness, safety, and dosage of fosinopril in children aged 6 to 16 with hypertension, utilizing a double-blind, placebo-controlled design across 78 clinical sites.
- The trial involved four phases: screening, dose-response, placebo withdrawal, and an open-label safety phase, finding that all tested doses effectively lowered systolic blood pressure in participants.
- Results showed a significant difference in blood pressure increase during the placebo withdrawal, indicating fosinopril's effectiveness, while it was generally well tolerated with few serious side effects, suggesting that starting doses for children should be lower than those for adults.
[The efficacy of using blood-saving technologies in operations on the heart and aorta].
Anesteziol Reanimatol
September 2000
Application of blood-saving methods during open-heart and aorta surgeries is discussed as exemplified by 86 patients. Platelet-rich plasma was prepared before surgery and infused during heart valve replacement, which decreased the postoperative blood loss 1.5 times.
View Article and Find Full Text PDFA study is presented of 582 patients with acute viral-bacterial pneumonia in those with a history of influenza and acute respiratory disease (ARD). Protracted course of the disease was observed in 121 (20.8%) and 461 (79.
View Article and Find Full Text PDFIn experimental influenza infection in mice, inhibition of generation of antibody and antibody-producing cells was observed against reduced activity of T-suppressors and activation of T-helpers. These data indicate that the immunosuppressive effect of influenza virus is associated with inhibition of some other elements in the lymphocyte T-system rather than T-helpers.
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