Publications by authors named "Zharkin A"

Aim: To conduct a long-term epidemiological trial to specify prevalence and significance of risk factors (RF) of atherosclerosis (AS) and IHD related and unrelated with reproductive system in fertile women.

Material And Methods: 962 premenopausal women entered the trial. They were examined for RF of IHD and AS as well as some conditions of the reproductive system induced by oral contraceptives, replacement hormonal therapy, postmorbid period of OPH-gestosis, uterine myoma, ovarian failure.

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The purpose of this study was to develop an effective pathogenetically validated method for the treatment of puerperants with pyoseptic diseases, making use of reflex therapy, and clinical assessment of this method. The study has involved 190 puerperants, in 50 of them the postpartum period ran a normal course and the rest 140 developed pyoseptic complications. Case histories were analyzed, clinical and laboratory tests (blood proteins, Mancini's test for immunoglobulins, Dorofeichuk's blood plasma lysozyme test) were carried out.

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Acupuncture was carried out for 3-6 days in the course of preparation to labor of 80 pregnant women at risk of developing labor activity abnormalities. Pulmonary, renal, gastric meridians, anteromedian and auricular points were used. Acupuncture was conductive to improvement of the autonomic nervous system activity with the predominance of the cholinergic component.

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The efficacy of the routine anti-inflammatory and resolving therapy and the rehabilitation method which is based on the principle of exposing the patients to physical factors with due regard to the specific features of menstrual cyclic processes in the female body was studied in 170 patients with chronic non-specific salpingo-oophoritis during their steady-state remission. The efficiency was checked up by using general clinical, instrumental, and laboratory tools and examining viscerocutaneous and vegetative reflexes. It was concluded that it was impossible to achieve a full restoration of specific functions in the patients without normalizing the cyclic changes in homeostasis, autonomically endocrine regulation which should be the major matter of a physician's therapeutic efforts.

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Eleven patients with small-intestinal nodular lymphoid hyperplasia combined with immunodeficiency were studied; special reference was made to the clinical appearance as well as roentgenologic, endoscopic, electron-microscopic, histochemical and immunomorphologic evidence of this condition. It is suggested that the demonstrated morphologic and enzymatic changes in the lymphoid apparatus reflect a disturbance at the immunogenetic level where lymphocyte B function is connected with adequate immunoglobulin synthesis by plasma cells. This disturbance accounts for excessive lymphocyte proliferation within the intestinal wall and lymph nodes, and even the production of inadequate, or sometimes abnormal, immunoglobulins by plasma cells.

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An analysis of diagnosis and treatment of 8 patients with malignant tumors of the small intestine is presented, 1.7% of all the cases being new formations of the gastrointestinal tract. The timely diagnosis of small intestine tumor can be made by the employment of probe enterography allowing to establish the character and localization of the pathological process.

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