Publications by authors named "Zhaoyu Jia"
Article Synopsis
- Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation in the joints, with a particular focus on the role of a compound called columbianadin (CBN) in regulating this inflammation.
- The study investigated how CBN affects abnormal growth and behavior of synoviocytes (joint cells) by targeting a protein called vimentin, which is involved in cell migration and proliferation.
- Results showed that CBN can inhibit the growth and movement of these cells, likely by binding to vimentin, thereby reducing joint swelling and damage in a mouse model of RA.
Article Synopsis
- Scientists studied how cells in the uterus change when a woman becomes pregnant.
- They used a special technique to look at these cells and found that they start using more proteins and fats as energy.
- The research showed that different types of these cells are active in different ways, which helps understand how the pregnancy process works.
The uterine epithelium undergoes a dramatic spatiotemporal transformation to enter a receptive state, involving a complex interaction between ovarian hormones and signals from stromal and epithelial cells. Redox homeostasis is critical for cellular physiological steady state; emerging evidence reveals that excessive lipid peroxides derail redox homeostasis, causing various diseases. However, the role of redox homeostasis in early pregnancy remains largely unknown.
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