Influence of Tiapride and Topiramate on Tic Severity and Behavioral/Emotional Problems in Children with Tourette Syndrome: A Retrospective Study.

Objectives: To investigate the effect of tiapride and topiramate on patients with Tourette syndrome (TS).

Methods: This retrospective analysis included 126 children diagnosed with TS at Children's Hospital of Chongqing Medical University from 2019 to 2021, with treatment including tiapride (n = 60) and topiramate (n = 66). Their tic severity values were assessed with the Yale Global Tic Severity Scale (YGTSS).

Activation of the AKT/GSK-3β/β-catenin pathway via photobiomodulation therapy promotes neural stem cell proliferation in neonatal rat models of hypoxic-ischemic brain damage.

Background: Hypoxic-ischemic brain damage (HIBD) significantly affects neurodevelopment in infants and is a leading cause of severe neurological morbidity and mortality in neonates. Our previous study found that photobiomodulation therapy (PBMT) improves the impaired spatial learning and memory of HIBD rat models. However, the neuroprotective mechanism conferred by PBMT in HIBD is unclear.

Seasonality and Trend Forecasting of Tuberculosis Incidence in Chongqing, China.

Tuberculosis (TB) is a global infectious disease and one of the ten leading causes of death worldwide. As TB incidence is seasonal, a reliable forecasting model that incorporates both seasonal and trend effects would be useful to improve the prevention and control of TB. In this study, the X12 autoregressive integrated moving average (X12-ARIMA) model was constructed by dividing the sequence into season term and trend term to forecast the two terms, respectively.

Predicting trend of early childhood caries in mainland China: a combined meta-analytic and mathematical modelling approach based on epidemiological surveys.

Early childhood caries (ECC) is the most common chronic disease in young children. A reliable predictive model for ECC prevalence is needed in China as a decision supportive tool for planning health resources. In this study, we first established the autoregressive integrated moving average (ARIMA) model and grey predictive model (GM) based on the estimated national prevalence of ECC with meta-analysis from the published articles.

Prevalence and care index of early childhood caries in mainland China: evidence from epidemiological surveys during 1987-2013.

Early childhood caries (ECC) is the most common chronic disease in young children. Its reported prevalence varies greatly across China. This systematic review aimed to explore the epidemiological characteristics of ECC in mainland China from 1987 to 2013.