Especially, the processing and utilization of biomass-based material is closely related to the vessel, e.g. the flow of vapour and additive.
View Article and Find Full Text PDFTraditional coal spontaneous combustion (CSC) inhibitors, while effective, have limitations such as frequent application or short-term efficacy. To this end, we developed a slow-release and water-soluble synergistic inhibitor (SWSI) to achieve long-term CSC inhibition. The SWSI was formulated by integrating synergistic antioxidants (SA) composed of ascorbic acid (AsA) and Fe-superoxide dismutase (Fe-SOD) dissolved in a super absorbent polymer (SAP) encapsulated within hydrogel microcapsules.
View Article and Find Full Text PDFAmonton's law of friction states that the friction force is proportional to the normal force in magnitude, and the slope gives a constant friction coefficient. In this work, with molecular dynamics simulation, we study how the kinetic friction at the nanoscale deviates qualitatively from the relation. Our simulation demonstrates that the friction behavior between a nanoscale AFM tip and an elastic graphene surface is regulated by the coupling of the applied normal force and the substrate deformability.
View Article and Find Full Text PDFBackground: The metabolic characteristics of premature ovarian insufficiency (POI), a reproductive endocrine disease characterized by abnormal sex hormone metabolism and follicle depletion, remain unclear. Metabolomics is a powerful tool for exploring disease phenotypes and biomarkers. This study aims to identify metabolic markers and construct diagnostic models, and elucidate the underlying pathological mechanisms for POI.
View Article and Find Full Text PDFIntroduction: Root cutting is an important process in garlic field harvesting but is the weakest link in the full mechanization of garlic production. To improve the current situation of technological backwardness and poor operational quality of mechanized garlic root-cutting in the main garlic-producing regions of China, this study combined the physical characteristics and agronomic requirements of garlic plants, and proposed an innovative floating root-cutting technology for garlic combine harvesters that enables the top alignment of bulb, adaptive profiling floating of cutter, and embedded cutting of roots.
Methods: Through the kinematic analysis of the floating cutting process, the coordinate equations of the initial contact point of the bulb, the mathematical model of the floating displacement of the cutting component.
The autofluorescence phenomenon is an inherent characteristic of lignified cells. However, in the case of (), the autofluorescence is nearly imperceptible during occasional fluorescence observations. The aim of this study is to investigate the mechanism behind the quenching of lignin's autofluorescence in by conducting associated experiments.
View Article and Find Full Text PDFPremature ovarian insufficiency (POI) is a reproductive endocrine disorder characterized by infertility and perimenopausal syndrome, with a highly heterogeneous genetic etiology and its mechanism is not fully understood. Therefore, we utilized Oxford Nanopore Technology (ONT) for the first time to characterize the full-length transcript profile, and revealed biomarkers, pathway and molecular mechanisms for POI by bioinformatics analysis and machine learning. Ultimately, we identified 272 differentially expressed genes, 858 core genes, and 25 hub genes by analysis of differential expression, gene set enrichment, and protein-protein interactions.
View Article and Find Full Text PDFGarlic root cutting is generally performed manually; it is easy for the workers to sustain hand injuries, and the labor efficiency is low. However, the significant differences between individual garlic bulbs limit the development of an automatic root cutting system. To address this problem, a deep learning model based on transfer learning and a low-cost computer vision module was used to automatically detect garlic bulb position, adjust the root cutter, and cut garlic roots on a garlic root cutting test bed.
View Article and Find Full Text PDFTraditional manual garlic root cutting is inefficient and can cause food safety problems. To develop food processing equipment, a novel and accurate object detection method for garlic using deep learning-a convolutional neural network-is proposed in this study. The you-only-look-once (YOLO) algorithm, which is based on lightweight and transfer learning, is the most advanced computer vision method for single large object detection.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
July 2022
In response to the coronavirus disease 2019 (COVID-19) pandemic, various countries have sought to control COVID-19 transmission by introducing non-pharmaceutical interventions. Restricting population mobility, by introducing social distancing, is one of the most widely used non-pharmaceutical interventions. Although similar population mobility restriction interventions were introduced, their impacts on COVID-19 transmission are often inconsistent across different regions and different time periods.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
December 2023
Knowledge distillation (KD) transfers discriminative knowledge from a large and complex model (known as teacher) to a smaller and faster one (known as student). Existing advanced KD methods, limited to fixed feature extraction paradigms that capture teacher's structure knowledge to guide the training of the student, often fail to obtain comprehensive knowledge to the student. Toward this end, in this article, we propose a new approach, synchronous teaching knowledge distillation (STKD), to integrate online teaching and offline teaching for transferring rich and comprehensive knowledge to the student.
View Article and Find Full Text PDFBacteriophage Q protein engages σ-dependent paused RNA polymerase (RNAP) by binding to a DNA site embedded in late gene promoter and renders RNAP resistant to termination signals. Here, we report a single-particle cryo-electron microscopy (cryo-EM) structure of an intact Q-engaged arrested complex. The structure reveals key interactions responsible for σ-dependent pause, Q engagement, and Q-mediated transcription antitermination.
View Article and Find Full Text PDFPasteurella multocida is the causative agent of fowl cholera, and florfenicol (FF) has potent antibacterial activity against P. multocida and is widely used in the poultry industry. In this study, we established a P.
View Article and Find Full Text PDFMultidrug resistance (MDR) due to overexpression of P-glycoprotein (P-gp) is a major obstacle that hinders the treatment of hepatocellular carcinoma (HCC). It has been shown that miR-375 inhibits P-gp expression via inhibition of astrocyte elevated gene-1 (AEG-1) expression in HCC, and induces apoptosis in HCC cells by targeting AEG-1 and YAP1. In this study, we prepared lipid-coated hollow mesoporous silica nanoparticles (LH) containing doxorubicin hydrochloride (DOX) and miR-375 (LHD/miR-375) to deliver the two agents into MDR HCC cells in vitro and in vivo.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2015
Cherubism is a rare, nonneoplastic, self-limiting fibro-osseous that occurs in children. Affected children usually appear normal at birth. Lesions are characterized by the replacement of bone with fibrovascular tissue containing many multinucleated giant cells.
View Article and Find Full Text PDFIn this paper, one-dimensional (1D) mesoporous single-crystalline Co₃O₄ nanobelts are synthesized by a facile hydrothermal method followed by calcination treatment. The as-prepared nanobelts have unique mesoporous structures, which are constructed by many interconnected nanocrystals with sizes of about 20-30 nm. And typical size of the nanobelts is in the range of 100-300 nm in width and up to several micrometers in length.
View Article and Find Full Text PDFShanghai Kou Qiang Yi Xue
October 2006
Purpose: This study was designed to determine the consistency of craniofacial measurements using spiral computed tomography volume rendering by computer systems and sliding caliper.
Methods: The study population consisted of 12 cadaver heads which were examined with spiral CT. The archived CT data were transferred to a workstation, and 3D-CT volume rendered images were generated using computer graphics tools.