AtSNU13 modulates pre-mRNA splicing of RBOHD and ALD1 to regulate plant immunity.

Pre-mRNA splicing is a significant step for post-transcriptional modifications and functions in a wide range of physiological processes in plants. Human NHP2L binds to U4 snRNA during spliceosome assembly; it is involved in RNA splicing and mediates the development of human tumors. However, no ortholog has yet been identified in plants.

Stereoselective Crystallization of Chiral Pharmaceuticals Aided by Cellulose Derivatives through Helical Pattern Matching.

Stereoselective inhibition aided by "tailor-made" polymeric additives is an efficient approach to obtain enantiopure compounds through conglomerate crystallization. The chemical and configurational match between the side groups of polymers and the molecules of undesired enantiomer is considered to be a necessary condition for successful stereoseparation. Whereas in this contribution, we present an effective resolution of chiral pharmaceuticals by using cellulose acetates as the additives, which stereoselectively reside on the specific crystal faces of one enantiomer and inhibit its crystal nucleation and growth through helical pattern and supramolecular interaction complementarity.

S100 calcium‑binding protein A16 suppresses the osteogenic differentiation of rat bone marrow mesenchymal stem cells by inhibiting SMAD family member 4 signaling.

Osteogenesis is a complex process of bone formation regulated by various factors, yet its underlying molecular mechanisms remain incompletely understood. The present study aimed to investigate the role of S100A16, a novel member of the S100 protein family, in the osteogenic differentiation of rat bone marrow mesenchymal stem cells (BMSCs) and uncover a novel Smad4-mitogen-activated protein kinase (MAPK)/Jun N-terminal kinase (JNK) signaling axis. In the present study, the expression level of S100A16 in bone tissues and BMSCs from ovariectomized rats was evaluated and then the impact of S100A16 silencing on osteogenic differentiation was examined.

Plant Biostimulant as an Environmentally Friendly Alternative to Modern Agriculture.

Ensuring the safety of crop production presents a significant challenge to humanity. Pesticides and fertilizers are commonly used to eliminate external interference and provide nutrients, enabling crops to sustain growth and defense. However, the addition of chemical substances does not meet the environmental standards required for agricultural production.

Rational Design of F-Modified Polyester Electrolytes for Sustainable All-Solid-State Lithium Metal Batteries.

Solid polymer electrolytes (SPEs) are one of the most practical candidates for solid-state batteries owing to their high flexibility and low production cost, but their application is limited by low Li conductivity and a narrow electrochemical window. To improve performance, it is necessary to reveal the structure-property relationship of SPEs. Here, 23 fluorinated linear polyesters were prepared by editing the coordination units, flexible linkage segments, and interface passivating groups.

Dormancy and double-activation strategy for construction of high-performance mixed-matrix membranes.

Mixed-matrix membranes (MMMs) have the potential for energy-efficient gas separation by matching the superior mass transfer and anti-plasticization properties of the fillers with processability and scaling up features of the polymers. However, construction of high-performance MMMs has been prohibited due to low filler-loading and the existence of interfacial defects. Here, high MOF-loaded, i.

Robust small area estimation for unit level model with density power divergence.

Unit level model is one of the classical models in small area estimation, which plays an important role with unit information data. Empirical Bayesian(EB) estimation, as the optimal estimation under normal assumption, is the most commonly used parameter estimation method in unit level model. However, this kind of method is sensitive to outliers, and EB estimation will lead to considerable inflation of the mean square error(MSE) when there are outliers in the responses yij.

Self-Assembly and In Situ Quaternization of Triblock Bottlebrush Block Copolymers via Organized Spontaneous Emulsification for Effective Loading of DNA.

Microspheres bearing large pores are useful in the capture and separation of biomolecules. However, pore size is typically poorly controlled, leading to disordered porous structures with limited performances. Herein, ordered porous spheres with a layer of cations on the internal surface of the nanopores are facilely fabricated in a single step for effective loading of DNA bearing negative charges.

Confining Water Nanotubes in a CuO-Based Metal-Organic Framework for Propylene/Propane Separation with Record-High Selectivity.

Energy-efficient separation of propylene (CH)/propane (CH) is in high demand for the chemical industry. However, this process is challenging due to the imperceptible difference in molecular sizes of these gases. Here, we report a continuous water nanotube dedicatedly confined in a CuO-based metal-organic framework (MOF) that can exclusively adsorb CH over CH with a record-high selectivity of 1570 (at 1 bar and 298 K) among all the porous materials.

Rapid Fabrication of High-Permeability Mixed Matrix Membranes at Mild Condition for CO Capture.

Mixed matrix membranes (MMMs), conjugating the advantages of flexible processing-ability of polymers and high-speed mass transfer of porous fillers, are recognized as the next-generation high-performance CO capture membranes for solving the current global climate challenge. However, controlling the crystallization of porous metal-organic frameworks (MOFs) and thus the close stacking of MOF nanocrystals in the confined polymer matrix is still undoable, which thus cannot fully utilize the superior transport attribute of MOF channels. In this study, the "confined swelling coupled solvent-controlled crystallization" strategy is employed for well-tailoring the in-situ crystallization of MOF nanocrystals, realizing rapid (<5 min) construction of defect-free freeway channels for CO transportation in MMMs due to the close stacking of MOF nanocrystals.

Degradation of PAHs in soil by activated persulfate system with activated carbon supported iron-based bimetal.

We developed a material of activated carbon (AC)-supported highly active iron-based bimetal (iron-copper bimetal/AC, Fe-Cu/AC) with high efficiency for polycyclic aromatic hydrocarbons (PAHs) degradation in soil by activating persulfate, benefiting from the synergistic effect that the characteristics of AC with porous carbon backbone, multiple active functional groups, high loading capacity and the characteristics of FeCu bimetal with high activity. The addition of Cu to the Fe-based/AC activator not only improved the dispersibility of Fe particles but also maintained the stability of the metal in the Fe-Cu/AC. The thermal activation (50 °C) promoted the degradation of PAHs by the Fe-Cu/AC-activated SO system.

Insight into boron-doped biochar as efficient metal-free catalyst for peroxymonosulfate activation: Important role of -O-B-O- moieties.

In recent years, metal-free catalysts for persulfate-mediated oxidation processes have been widely applied to remove contaminants in the aquatic environment. Herein, a simple pyrolysis approach was used to synthesize the boron doped biochars (B@TBCs) derived from boric acid mixed with tea seed shells powders. The obtained B@TBCs exhibited fantastic capability to boost PMS (0.

Comparison of σ/ π-hole aerogen-bonding interactions based on CH···NgOX (Ng = Kr, Xe; X = F, Cl, Br) complexes.

The geometric structure, energy properties, and electronic properties of the aerogen-bonding interaction formed by CH and NgOX (Ng = Kr, Xe; X = F, Cl, Br) have been studied at the B2PLYP-D3(BJ)/ aug-cc-pVTZ (PP) level. Two kinds of aerogen-bonding interactions were observed among the title systems: the σ-hole and the π-hole complexes. The σ-hole aerogen-bonding complex has a binding energy in the range of - 6.

Anion Regulates Topological Porous Coordination Polymers into the Acetylene Trap.

The development of efficient porous absorbents with high uptake and selectivity remains a great challenge, especially for the recovery of acetylene (CH) from its carbon dioxide (CO)-containing mixtures. Here, we propose and report an anion-planting strategy for regulating the topological porous coordination polymers (PCPs) into the CH trap. The three electronegative anions SiF, TiF, and ZrF, in addition to the ligand of 3,5-di(1H-imidazol-1-yl)benzoic acid () and Cu ion, were employed to construct highly porous PCPs (, , and ) with varied window aperture.

Three types of noncovalent interactions studied between pyrazine and XF.

Three types noncovalent interactions (type I, II and III) between pyrazine (CHN) and XF (X = F, Cl, Br, and I) have been discovered at the MP2/aug-cc-pVTZ level. TypeI is σ-hole interaction between the positive site on the halogen X of XF and the negative site on one of the pyrazine nitrogens. Type II is counterintuitive σ-hole interaction driven by polarization between the positive site on the halogen X of XF and a portion of the pyrazine ring.

Tuning organic crystal chirality by the molar masses of tailored polymeric additives.

Hierarchically ordered chiral crystals have attracted intense research efforts for their huge potential in optical devices, asymmetric catalysis and pharmaceutical crystal engineering. Major barriers to the application have been the use of costly enantiomerically pure building blocks and the difficulty in precise control of chirality transfer from molecular to macroscopic level. Herein, we describe a strategy that offers not only the preferred formation of one enantiomorph from racemic solution but also the subsequent enantiomer-specific oriented attachment of this enantiomorph by balancing stereoselective and non-stereoselective interactions.

Highly Efficient and Chemoselective Hydrogenation of Nitro Compounds into Amines by Nitrogen-Doped Porous Carbon-Supported Co/Ni Bimetallic Nanoparticles.

A novel Co/Ni bimetallic nanoparticle supported by nitrogen-doped porous carbon (NPC), Co/Ni@NPC-700, exhibits high conversion, chemoselectivity, and recyclability in the hydrogenation of 16 different nitro compounds into desired amines with hydrazine hydrate under mild conditions. The synergistic effects of Co/Ni bimetal nanoparticles and the NPC-supported porous honeycomb structure with more accessible active sites may be responsible for the high catalytic hydrogenation performance.

Cu Nanoclusters Anchored on the Metal-Organic Framework for the Hydrolysis of Ammonia Borane and the Reduction of Quinolines.

Free-access active sites created and the interaction regulated between them and substrates during the heterogeneous catalysis process are crucial, which remain a great challenge. In this work, in suit reduced to afford naked Cu nanoparticles (NPs) have been anchored on the metal-organic framework (MOF), NH-MOF, to form Cu-NH-MOF. The strategy can precisely control the Cu NP formation with small size and uniform distribution.

Noncovalently Functionalized Commodity Polymers as Tailor-Made Additives for Stereoselective Crystallization.

Stereoselective inhibition of the nucleation and crystal growth of one enantiomer aided by "tailor-made" polymeric additives is an efficient method to obtain enantiopure compounds. However, the conventional preparation of polymeric additives from chiral monomers are laborious and limited in structures, which impedes their rapid optimization and applicability. Herein, we report a "plug-and-play" strategy to facilitate synthesis by using commercially available achiral polymers as the platform to attach various chiral small molecules as the recognition side-chains through non-covalent interactions.

Fluorinated Poly-oxalate Electrolytes Stabilizing both Anode and Cathode Interfaces for All-Solid-State Li/NMC811 Batteries.

The relatively narrow electrochemical steady window and low ionic conductivity are two critical challenges for Li -conducting solid polymer electrolytes (SPE). Here, a family of poly-oxalate(POE) structures were prepared as SPE; among them, POEs composed from diols with an odd number of carbons show higher ionic conductivity than those composed from diols with an even number of carbons, and the POE composed from propanediol (C5-POE) has the highest Li conductivity. The HOMO (highest occupied molecular orbital) electrons of POE were found located on the terminal units.

Structural characteristics and evolution of the "international trade-carbon emissions" network in equipment manufacturing industry: international evidence in the perspective of global value chains.

The objective of this paper is to analyze structural characteristics and the evolution of "international trade-carbon emissions" network in the equipment manufacturing industry. To do so, we construct four kinds of networks, namely export trade network (E network), export implied carbon emission network (EC network), foreign value-added network (FVA network), and foreign value-added implied carbon emission network (FVAC network) for the said industry. The data obtained from world-input-output table and social network analysis method was used for empirical analysis.