Enhanced Digital Light Processing-Based One-Step 3-Dimensional Printing of Multifunctional Magnetic Soft Robot.

Soft structures driven by magnetic fields exhibit the characteristics of being unencumbered and rapidly responsive, enabling the fabrication of various soft robots according to specific requirements. However, soft structures made from a single magnetic material cannot meet the multifunctional demands of practical scenarios, necessitating the development of soft robot fabrication technologies with composite structures of diverse materials. A novel enhanced digital light processing (DLP) 3-dimensional (3D) printing technology has been developed, capable of printing composite magnetic structures with different materials in a single step.

Complications of Polyacrylamide Hydrogel Facial Injection: Clinical Studies and Literature Review.

Background: Polyacrylamide hydrogel (PAHG) is a new biomaterial that emerged in the last century and has been widely used in human filler procedures, such as injectable breast augmentation and facial contour improvement. However, as the implantation time of the material increases, various complications have been reported, which reflects that the safety of this material has not been adequately studied. Therefore, a more in-depth experimental analysis becomes particularly important.

Harnessing the Power of Photosynthesis: from Current Engineering Strategies to Cell Factory Applications.

Photosynthesis has garnered significant interest due to its potential for retrofitting and its intrinsic enzyme-mediated metabolic processes, which can convert carbon dioxide (CO) into biomass powered by solar energy. However, natural photosynthesis is limited by factors such as low photosynthetic efficiency and constraints on the range of output products. To address these issues, researchers have developed various strategies for designing and engineering photosynthetic systems.

The Correlation between Serum Procalcitonin and C-Reactive Protein and Main Complications After Endoscopic Retrograde Cholangiopancreatography.

Background: The aim of this study was to explore the clinical value of serum procalcitonin (PCT) and C-reactive protein (CRP) levels in evaluating complications after endoscopic retrograde cholangiopancreatography (ERCP) in patients with common bile duct (CBD) stones.

Methods: Patients who were diagnosed with CBD stones and underwent ERCP from December 2021 to December 2023 were selected as the study subjects. According to whether postoperative complications occurred, they were divided into complication group (n = 28) and non-complication group (n = 132).

Cross-Shaped Heat Tensor Network for Morphometric Analysis Using Zebrafish Larvae Feature Keypoints.

Deep learning-based morphometric analysis of zebrafish is widely utilized for non-destructively identifying abnormalities and diagnosing diseases. However, obtaining discriminative and continuous organ category decision boundaries poses a significant challenge by directly observing zebrafish larvae from the outside. To address this issue, this study simplifies the organ areas to polygons and focuses solely on the endpoint positioning.

A highly sensitive flexible sensor based on the MXene/αFeO composite structure applied for the simultaneous detection of glucose and uric acid.

Sensors based on inorganic nanomaterials for the detection of human body fluids show great potential in real-time detection and treatment of human health due to their advantages of small size and easy to wear. Nevertheless, most of the existing sensors have the disadvantage of detecting relatively simple substances and suffer from low sensitivity, which undermines their practical applicability in body fluids detection. In this study, based on the transition metal carbide (TiCT, MXene)/αFeO grid composite structure, a highly sensitive flexible sensor is proposed, which can realize accurate and simultaneous detection of glucose and uric acid (UA) concentration.

TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response.

Objective: Abnormal expression of T-lymphokine-activated killer cell-originated protein kinase (TOPK) was reported to be closely related to the resistance of prostate cancer to radiotherapy and to targeted drug resistance in lung cancer. However, the role of TOPK inhibition in enhancing radiosensitivity of colorectal cancer (CRC) cells is unclear. This study aimed to evaluate the radiosensitization of TOPK knockdown in CRC cells.

Traceability of gushing water in the MiddleRoute of the South-to-North Water Diversion (Beijing section) through the river area.

To trace the origin of the gushing water in the riverine area of the Beijing section of The Middle Route of South-to-North Water Diversion Project, a dataset was established comprising water chemistry, three-dimensional fluorescence spectra, and stable isotopes for different water bodies. Results indicated significant differences in Electrical Conductivity (EC), Total Dissolved Solids (TDS), and Ca concentration among the gushing water, river water, and the water from the Middle Route of South-to-North Water Diversion Project (MRSD). Analysis using parallel factor analysis (PARAFAC) and fluorescence index revealed that dissolved organic matter (DOM) in the MRSD mainly originated from endogenous sources, while the river water and gushing water showed influences from both endogenous and exogenous sources.

Metabolites and metabolic pathway analysis of sulfadimidine in carp (Cyprinus carpio) based on UHPLC-Q-orbitrap HRMS.

Sulfadimidine (SM) is an N-substituted derivative of p-aminobenzenesulfonyl structure. This study aimed to analyze the metabolism of SM in carp (Cyprinus carpio). The carps were fed with SM at a dose of 200 mg/(kg · bw) and then killed.

One step accurate phase demodulation from a closed fringe pattern with the convolutional neural network HRUnet.

Retrieving a phase map from a single closed fringe pattern is a challenging task in optical interferometry. In this paper, a convolutional neural network (CNN), HRUnet, is proposed to demodulate phase from a closed fringe pattern. The HRUnet, derived from the Unet model, adopts a high resolution network (HRnet) module to extract high resolution feature maps of the data and employs residual blocks to erase the gradient vanishing in the network.

A conserved methyltransferase active site residue of Zika virus NS5 is required for the restriction of STING activation and interferon expression.

Zika virus (ZIKV) is a re-emerging RNA virus and causes major public health events due to its link to severe neurological complications in foetuses and neonates. The cGAS-STING signalling pathway regulates innate immunity and plays an important role in the invasion of DNA and RNA viruses. This study reveals a distinct mechanism by which ZIKV restricts the cGAS-STING signalling to repress IFN-β expression.

Hyaluronic acid filler-induced vascular occlusion-Three case reports and overview of prevention and treatment.

Background: Vascular occlusion induced by hyaluronic acid injections is rare, but can lead to severe adverse events, including necrosis, blindness, and cerebral infarction.

Objective: This study aims to explore methods of reducing the risk of complications such as embolism induced by hyaluronic acid injection, and to study the impact of comprehensive systematic treatment on the prognosis of patients with hyaluronic acid embolism.

Methods: The clinical data of three female patients with vascular occlusion due to hyaluronic acid injection was analyzed.

Evaluation of different diagnostic methods for spinal tuberculosis infection.

Background And Purpose: Tuberculosis (TB) is the most fatal infectious disease worldwide. Approximately 24.6% of tuberculosis cases are extrapulmonary and predominantly affect the spine.

Development of a Diagnostic Model for Differentiating Tuberculous Spondylitis and Pyogenic Spondylitis With MRI: A Multicenter Retrospective Observational Study.

Study Design: Multicenter retrospective observational study.

Objective: This study aimed to distinguish tuberculous spondylitis (TS) from pyogenic spondylitis (PS) using magnetic resonance imaging (MRI). Further, a novel diagnostic model for differential diagnosis was developed.

Investigation of water quality and aquatic ecological succession of a newly constructed river replenished by reclaimed water in Beijing.

The potential to create new ecosystems in rivers is possible through the use of reclaimed water as a replenishment source, although the long-term effects of this method are unknown. In this study, the water quality and aquatic ecological evolution of a newly constructed river replenished by reclaimed water in Beijing (the Jing River) were investigated, and the conventional water quality, phytoplankton indicators, and submerged plant growth conditions from October 2018 to December 2020 were analyzed. Spearman's correlation and redundancy analysis between possible influential environmental factors and algal indicators were conducted.

Variation and characterization of prometryn in oysters (Crassostrea gigas) after seawater exposure.

Prometryn (PRO) is frequently detected in shellfish of international trade among triazine herbicides because of its wide application in agriculture and aquaculture worldwide. Nevertheless, the variations of PRO remain unclear in aquatic organisms, which affect the accuracy of their food safety risk assessment. In the present study, the tissue-specific accumulation, biotransformation, and potential metabolic pathway of PRO were reported in oyster species Crassostrea gigas for the first time.

Widely Targeted HPLC-MS/MS Metabolomics Analysis Reveals Natural Metabolic Insights in Insects.

Insect metabolites play vital roles in regulating the physiology, behavior, and numerous adaptations of insects, which has contributed to them becoming the largest class of Animalia. However, systematic metabolomics within the insects is still unclear. The present study performed a widely targeted metabolomics analysis based on the HPLC-MS/MS technology to construct a novel integrated metabolic database presenting comprehensive multimetabolite profiles from nine insect species across three metamorphosis types.

Structure-Performance relationship guided design and strategic synthesis of lithiated oxa-graphene for high lithium storage.

Graphene derivative materials are widely used as anode component in lithium-ion batteries. However, there is still a lack of reliable and foresighted guides helpful for designing high-performance graphene-based electrode materials. To this end, we strategically chose challenging graphite fluoride as starting material for the derivatization of graphene in order to exclude interference factors.

MARK3 kinase: Regulation and physiologic roles.

Microtubule affinity-regulating kinase 3 (MARK3), a member of the MARK family, regulates several essential pathways, including the cell cycle, ciliated cell differentiation, and osteoclast differentiation. It is important to understand the control of their activities as MARK3 contains an N-terminal serine/threonine kinase domain, ubiquitin-associated domain, and C-terminal kinase-associated domain, which perform multiple regulatory functions. These functions include post-translational modification (e.

A Pyramid Semi-Autoregressive Transformer with Rich Semantics for Sign Language Production.

As a typical sequence to sequence task, sign language production (SLP) aims to automatically translate spoken language sentences into the corresponding sign language sequences. The existing SLP methods can be classified into two categories: autoregressive and non-autoregressive SLP. The autoregressive methods suffer from high latency and error accumulation caused by the long-term dependence between current output and the previous poses.

Egfr signaling promotes juvenile hormone biosynthesis in the German cockroach.

Background: In insects, an interplay between the activities of distinct hormones, such as juvenile hormone (JH) and 20-hydroxyecdysone (20E), regulates the progression through numerous life history hallmarks. As a crucial endocrine factor, JH is mainly synthesized in the corpora allata (CA) to regulate multiple physiological and developmental processes, including molting, metamorphosis, and reproduction. During the last century, significant progress has been achieved in elucidating the JH signal transduction pathway, while less progress has been made in dissecting the regulatory mechanism of JH biosynthesis.

Mechanism of downward migration of quinolone antibiotics in antibiotics polluted natural soil replenishment water and its effect on soil microorganisms.

Reclaimed water is widely concerned as an effective recharge of groundwater and surface water, but trace organic pollutants produced by traditional wastewater treatment plants (WWTPs) would cause environmental pollution (water and soil) during infiltration. Therefore, the effects of reclaimed water containing ofloxacin (OFL) and ciprofloxacin (CIP) in antibiotics polluted natural soil (APNS) were investigated by simulating soil aquifer treatment systems (SATs). The experiment results showed that OFL and CIP in water were adsorbed and microbially degraded mainly at 30 cm, and the concentration of OFL and CIP in soil increased with depth, which were mainly due to the desorption from APNS.