Publications by authors named "Zhaotang Gong"
Background: Linezolid-induced anemia (LI-AN) is a severe adverse reaction, but risk factors of the LI-AN for elderly patients have not been established.
Objectives: The objective of this study was to develop a nomogram capable of predicting LI-AN in elderly patients.
Design: This is a retrospective study to develop and validate a nomogram for anemia prediction in elderly patients treated with linezolid.
Article Synopsis
- The study aimed to evaluate the effectiveness and safety of Xuebijing injection (XBJI) for treating patients with severe sepsis, using data from 418 patients over a three-year period.
- Results showed no significant difference in 14-day mortality or hospital stay between patients treated with carbapenem alone and those given carbapenem with XBJI, although the combined treatment led to improved inflammatory markers and kidney/liver function.
- Although XBJI did not decrease mortality, it demonstrated benefits in reducing inflammation and protecting organ function in sepsis patients.
Piperlongumine (PL) has been showed to have multiple pharmacological activities. In this study, we reported the synthesis of three series of PL derivatives, and evaluation of their anti-inflammatory effects in both lipopolysaccharide (LPS)-induced Raw264.7 macrophages and a dextran sulfate sodium (DSS)-induced mouse model of colitis.
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