Publications by authors named "Zhaoru Huang"

Article Synopsis
  • This study looked at two types of tests, mNGS and tNGS, to see which one is better at finding germs in lung samples from kidney transplant patients.
  • Researchers found that mNGS was generally better than tNGS, especially at correctly identifying bacteria and viruses.
  • Even though both mNGS and tNGS did better than traditional tests, mNGS had higher sensitivity and true positive rates than tNGS.
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In this study, we described the design, synthesis, and biological evaluation of 1,3-diaryl-pyridones as vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. The 1,3-diaryl-pyridones were synthesized via Chan-Lam and Suzuki coupling reactions. Two representative compounds, 17 and 35h, displayed excellent enzymatic inhibitory activities, with IC50 values of 3.

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