Long non-coding RNA RBM5-AS1 promotes the aggressive behaviors of oral squamous cell carcinoma by regulation of miR-1285-3p/YAP1 axis.

The human genome encodes far more long non-coding RNA (lncRNA) genes than protein coding genes. However, the function of majority of the lncRNAs is poorly understood. Numerous lncRNAs were aberrantly expressed in various cancers and found to be associated with development and progression of cancer.

Expression of MIF, Beclin1, and LC3 in human salivary gland adenoid cystic carcinoma and its prognostic value.

Adenoid cystic carcinoma (ACC) is an uncommon salivary gland malignancy with a poor long-term prognosis. Clinical reports show the high rates of local recurrences and distant metastases. This study aimed to investigate the expression of MIF, Beclin1, and light-chain 3 (LC3) in salivary adenoid cystic carcinoma (SACC).

[Analysis of related factors affecting treatment results in 126 patients with oral and maxillofacial space infection].

Purpose: This study was aimed to retrospectively investigate the related factors of oral and maxillofacial space infection in 126 patients.

Methods: The clinical data of 126 patients with oral and maxillofacial space infection were collected from the Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Xinjiang Medical University during the period of 2015 to 2017. The clinical features (e.

Prognostic value of GLUT-1 expression in oral squamous cell carcinoma: A prisma-compliant meta-analysis.

Background: A variety of studies have evaluated the correlation between glucose transporter-1 (GLUT-1) expression and prognosis of oral squamous cell carcinoma (OSCC); however, the results were inconsistent and inconclusive. A meta-analysis was performed to assess the prognostic significance of GLUT-1 in OSCC.

Methods: Electronic databases of PubMed, Embase, and Web of Science were searched for relevant studies.

Kimura's disease: risk factors of recurrence and prognosis.

Objectives: The aim of this study was to evaluate risk factors for recurrence and prognosis of Kimura's disease.

Methods: In this study, 32 patients received surgery alone, surgery followed by steroids orally and surgery followed by radiotherapy respectively from 2003 to 2015 (male/female: 27/5, ages: 6-64 years). Retrieval of clinical data and follow-ups have been done.

[Expressions of interleukin-21 and interleukin-22 in Kimura's disease].

Objective: To investigate the expressions of interleukin (IL)-21 (IL-21) and IL-22 in patients with Kimura's disease (KD).

Methods: Expressions of IL-21 and IL-22 were examined immunohistochemically in 36 patients with KD and 7 normal controls. The integral absorbance (IA) of the two groups was compared.

[Expression of serum and urinary vascular endothelial growth factor-A and epidermal growth factor-like domain 7 in proliferating hemangioma treated with propranolol].

Objective: This study aims to investigate the expression levels of serum and urinary vascular endothelial growth factor-A (VEGF-A) and epidermal growth factor-like domain 7 (EGFL7) in proliferating infantile hemangioma patients under propranolol treatment.

Methods: Propranolol (0.5-2 mg x kg(-1)) was orally administered to 30 infants every day for 4-8 months.

Reconstruction of intraoral maxillary defect with buccal fat pad.

Unlabelled: The aim of the study was to evaluate the efficacy of the buccal fat pad (BFP) in the reconstruction of various intraoral maxillary defects as well as the success, anatomy, healing process, merits, demerits, and complications of this technique.

Materials And Methods: The study was conducted in the Oral and Maxillofacial Surgery Department of the First Affiliated Hospital of of Xinjiang Medical University, China, between 2007 and 2013. The BFP was used as a pedicled graft in the reconstruction of small to medium-sized intraoral defects in patients (18 men and 9 women) ranging in age from 2 to 70 years (mean age, 36 y).

Application of the submental island flap in the reconstruction of intraoral defects.

This study was conducted to evaluate the feasibility of clinically applying facial submental island flap in reconstruction of oral cancer ablation in residents of Xinjiang, China. A total of 21 patients with oral cavity cancer underwent surgical resection during 4.4 years.

[Preliminary study of chitosan/pcDNA-EGFP-TGFbeta1 nanoparticles used in the transfection of synovial-derived mesenchymal stem cells].

The objective of this study is to explore the application possibility of chitosan/pcDNA-EGFP-TGFPbeta1 nanoparticles in the transfection of synovial-derived mesenchymal stem cells (SDMSCs). Chitosan/pcDNA-EGFP-TGFbeta1 nanoparticles were fabricated through method of ionic crosslinking. The SDMSCs were harvested from rabbit joints and cultured to passage 3.

[Reconstruction of zygomatic-facial massive defect using modified bilobed flap after resection of skin cancer].

Objective: To investigate the clinical application of the modified bilobed flap in the reconstruction of zygomatic-facial massive defect after resection of skin cancer.

Methods: Between August 2009 and October 2011, 15 patients with skin cancer in the zygomatic-facial region underwent defect reconstruction using modified bilobed flaps after surgical removal. There were 12 males and 3 females, aged 52-78 years (mean, 64.

Overexpression of macrophage migration inhibitory factor in adenoid cystic carcinoma: correlation with enhanced metastatic potential.

Objectives: Adenoid cystic carcinoma (ACC) is a malignant tumor frequently arising in salivary glands with poor long-term prognosis due to high rates of local recurrences and distant metastases. Macrophage migration inhibitory factor (MIF) is a multi-functional cytokine and has recently emerged as a pro-tumorigenic factor in various cancers. This study is designed to investigate the expression status and functional significance of MIF in ACC.

Use of synovium-derived stromal cells and chitosan/collagen type I scaffolds for cartilage tissue engineering.

The objective was to investigate synovium-derived stromal cells (SDSCs) coupled with chitosan/collagen type I (CS/COL-I) scaffolds for cartilage engineering. CS/COL-I scaffolds were fabricated through freeze-drying and cross-linked by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. SDSCs were isolated from synovium and cultured onto CS/COL-I scaffolds, constructs of which were incubated in serum-free chondrogenic medium with sequential application of TGF-β1 and bFGF for up to 21 days and then implanted into nude mice.

[Expression of VEGF, EGFR, p16 in lip cancers and oral squamous cell carcinomas and their clinic significance].

Objective: To detect the expression of vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), p16 protein in lip cancers and oral squamous cell carcinoma (OSCC) as well as their clinicopathological significance.

Methods: Immunohistochemisty for expression VEGF, EGFR, P16 were carried out in 69 cases of lip cancers and OSCC.

Results: Expression of VEGF, EGFR, p16 protein in OSCC and lip cancers was respectively 71.