Publications by authors named "Zhaoqing Gong"
Long non-coding RNA has been shown to mediate the progression of polycystic ovary syndrome (PCOS). However, the role and mechanism of Prader-Willi region nonprotein coding RNA 2 (PWRN2) in PCOS progression remain unclear. In our study, Sprague-Dawley rat was injected with dehydroepiandrosterone to mimic PCOS rat models.
View Article and Find Full Text PDFCystic fibrosis (CF) is a life-threatening autosomal-recessive disease caused by mutations in a single gene encoding cystic fibrosis transmembrane conductance regulator (CFTR). CF effects multiple organs, and lung disease is the primary cause of mortality. The median age at death from CF is in the early forties.
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- - Myeloid-derived suppressor cells (MDSCs) are diverse cells that accumulate abnormally from myeloid cell differentiation and primarily function to suppress T cell activity, allowing tumors to evade the immune system.
- - The goal of immunotherapy is to enhance the immune system’s ability to fight tumors, but MDSCs pose a significant challenge by decreasing the effectiveness of these treatments and increasing tumor cell resistance.
- - This review examines the roles and mechanisms of MDSCs in the tumor microenvironment, explores immunotherapy strategies targeting MDSCs, and discusses potential advances in combining these therapies with immune checkpoint blockade for better cancer treatment outcomes.
Livestock farming development has become increasingly important in recent years. It not only provides us with meat nutrition and pet feeding but also increases the economic value by providing numerous employment opportunities, which improves our life quality. The livestock farming development depends on successful animal reproduction.
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