Study on the bearing performance of extra-long pile group foundation in accumulation slope under landslide effect.

This paper conducts a systematic study on the stress and deformation of ultra-long pile foundations in slope accumulations under sliding loads. Existing research lacks sufficient analysis of the bearing capacity and stability of pile groups under complex load conditions, increasing the risk of overall collapse of engineering structures under landslide effects. To address this, a numerical model of pile foundations in typical slope accumulations was established using finite element analysis software, based on practical engineering applications.

Polystyrene nanoplastics with different functional groups and charges have different impacts on type 2 diabetes.

Background: Increasing attention is being paid to the environmental and health impacts of nanoplastics (NPs) pollution. Exposure to nanoplastics (NPs) with different charges and functional groups may have different adverse effects after ingestion by organisms, yet the potential ramifications on mammalian blood glucose levels, and the risk of diabetes remain unexplored.

Results: Mice were exposed to PS-NPs/COOH/NH at a dose of 5 mg/kg/day for nine weeks, either alone or in a T2DM model.

Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma through the TRPA1-p38 MAPK pathway.

Increasing attention has been paid to the potential impact of microplastics (MPs) pollution on human health. MPs and phthalates coexist in the environment, however, the effects of exposure to MPs alone or to a combination of di-(2-ethylhexyl) phthalate (DEHP) and MPs on allergic asthma are unclear. This study investigates the effects of exposure to polystyrene microplastics (PS-MPs) or co-exposure with DEHP, on allergic asthma, and the underlying molecular mechanisms.

The effect and a mechanistic evaluation of polystyrene nanoplastics on a mouse model of type 2 diabetes.

Nanoplastics have become ubiquitous in the global environment and have attracted increasing attention. However, whether there is an influence between exposure to nanoplastics and diabetes is unclear. To determine the effects of exposure to Polystyrene nanoplastics (PS-NPs) and evaluate the underlying mechanisms, mice were orally exposed to PS-NPs at dosages of 1, 10, 30 mg/kg/day for 8 weeks, alone or combined with a high fat diet and streptozocin (STZ) injection.

Formaldehyde causes an increase in blood pressure by activating ACE/AT1R axis.

Previous studies suggest some link between formaldehyde exposure and harmful cardiovascular effects. But whether exposure to formaldehyde can cause blood pressure to rise, and if so, what the underlying mechanism is, remains unclear. In this study, C57BL/6 male mice were exposed to 0.

Insight into the purification of algael water by a novel flocculant with enhanced branched nanochitosan structure.

For improving inadequate nanostructural stability and promote algal removal efficiency, a novel nanochitosan-grafted flocculant (PAD-g-MNC) with an enhanced branched nanostructure and high molecular weight (MW) was fabricated via maleic anhydride acylation polymerization. Characterization results verified the successful synthesis of the flocculant and the formation of an irregular particle nanostructure. PAD-g-MNC exhibited superior algal and extracellular organic matter (EOM) removal and obtained the turbidity and chlorophyll-a removal rates of 93.

Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF.

Multi-walled carbon nanotubes (MWCNTs) and dibutyl phthalate (DBP) exist extensively in the environment, and they are easy to form compound pollution through π-π interactions in the environment. We investigate whether DBP, an environmental hormone disruptor, mediated by CNTs can more easily cross the blood-brain barrier, and whether DBP entering the brain has neurotoxic effects on the cells in the brain. Experimental subjects were 40 male Kunming (KM) mice randomly divided into 4 groups: the control group; the MWCNTs group; the DBP group; and the MWCNTs+DBP group.

Rapid Seismic Evaluation of Continuous Girder Bridges with Localized Plastic Hinges.

In seismic assessment of continuous girder bridges, plastic hinges form in bridge piers to dissipate seismic energy through nonlinear restoring forces. Considering temporal and spatial variations of ground motions, seismic evaluation of the bridges involves nonlinear stochastic vibration and expensive computation. This paper presents an approach to significantly increase the efficiency of seismic evaluation for continuous girder bridges with plastic hinges.

Lateral Vibration Control of Long-Span Small-Radius Curved Steel Box Girder Pedestrian Bridge with Distributed Multiple Tuned Mass Dampers.

Curved pedestrian bridges are important urban infrastructure with the desired adaptability to the landscape constraints and with aesthetic benefits. Pedestrian bridges feature thin cross-sections, which provide sufficient load capacities but lead to low natural frequencies that make the bridges susceptible to vibration under pedestrian excitation. This study investigates the lateral vibration of a curved bridge with a small radius down to 20 m, proposes an approach to mitigate the lateral vibration of bridges with large curvatures using distributed multiple tuned mass dampers (MTMD), and conducts in-situ bridge tests to evaluate the vibration mitigation performance.

Polystyrene microplastics affect learning and memory in mice by inducing oxidative stress and decreasing the level of acetylcholine.

Microplastics pollution has become a growing environmental concern, but its potential neurotoxic effects remain unknown. In this study, we determined the effects of exposure to polystyrene microplastics (micro-PS) on learning and memory, and explored the underlying mechanisms. Kunming mice were orally exposed to 0.

The reduction and fate of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in microbial fuel cell (MFC) during treatment of livestock wastewater.

The fate and removal efficiency of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in livestock wastewater by microbial fuel cell (MFC) was evaluated by High-throughput quantitative PCR. The results showed that 137 ARGs and 9 MGEs were detected in untreated livestock wastewater. The ARG number of macrolide-lincosamide-streptogramin group B (MLSB), tetracycline and sulfonamide were relatively higher.

Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice.

Microplastics (MPs) may have an impact on the reproductive development of humans and mammals. However, any effects of MPs exposure on male and female reproductive systems and fertility are still ambiguous. In this study, male and female C57BL/6 mice were exposed to saline or 0.

Phenanthrene induces autism-like behavior by promoting oxidative stress and mTOR pathway activation.

Autism is thought to be associated with both environmental and genetic factors. Phenanthrene (Phe) makes up a relatively high proportion of the low-ring polycyclic aromatic hydrocarbons. However, the association between exposure to Phe and Autism remain unclear.

The role and related microbial processes of Mn-dependent anaerobic methane oxidation in reducing methane emissions from constructed wetland-microbial fuel cell.

Anaerobic oxidation of methane (AOM) plays an important role in global carbon cycle and greenhouse gas emission reduction. In this study, an effective green technology to reduce methane emissions was proposed by introducing Mn-dependent anaerobic oxidation of methane (Mn-AOM) and microbial fuel cell (MFC) technology into constructed wetland (CW). The results indicate that the combination of biological methods and bioelectrochemical methods can more effectively control the methane emission from CW than the reported methods.

The fate of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) from livestock wastewater (dominated by quinolone antibiotics) treated by microbial fuel cell (MFC).

The removal characteristics of antibiotic resistance genes and mobile genetic elements from livestock wastewater (dominated by quinolone antibiotics) treated with MFC were evaluated by High-throughput quantitative (HT-qPCR). The results showed that 144 ARGs and 8 MEGs were detected in the livestock wastewater. After MFC treatment, the number of AGRs decreased as a whole, and the relative abundance of macrolide-lincosamide-streptogramin group B (MLSB) and aminoglycosider decreased by 62.

[Comparative study on arthroscopic anterior cruciate ligament reconstruction with transtibial technique and through anteromedial approach].

Objective: To compare the effectiveness of the arthroscopic anterior cruciate ligament (ACL) reconstruction with the transtibial technique and through anteromedial approach.

Methods: Between April 2008 and May 2012, 86 patients (86 knees) with ACL rupture underwent single bundle reconstruction with autogeneic hamstring tendons with the transtibial technique in 44 cases (group A) and through anteromedial approach in 42 cases (group B). There was no significant difference in age, gender, injury causes, injury to admission time, preoperative International Knee Documentation Committee (IKDC) score, and Lysholm score between 2 groups (P > 0.

[Cell apoptosis in atrophic skeletal muscle induced by immoblization in rabbits--an experimental study using TUNEL].

This experiment was designed to explore the correlation between the mechanism of immobilization-induced skeletal muscle atrophy and the apoptosis of muscular cells. The models of skeletal muscle atrophy induced by immobilization for different length of time were established according to Sievanen II methods. 24 rabbits, each of them having one hind leg fixed by the tubal plaster and the other one free as control, were randomly divided into four groups depending on time of fixation (3, 7, 14, and 28 days respectively).