Publications by authors named "Zhaojie Leng"
Cell Rep Med
November 2024
Article Synopsis
- The tumor microenvironment (TME) in glioblastoma (GBM) is highly immunosuppressive, making it resistant to current immunotherapies.
- A long non-coding RNA (LncRNA) called H19 produces an immune-related protein, H19-IRP, which enhances this immunosuppression by activating certain genes that attract immune-suppressing cells.
- A new circular RNA vaccine targeting H19-IRP shows promise in triggering an effective immune response against GBM, suggesting a potential treatment strategy for this aggressive cancer.
