Wafer-scale monolayer MoS film integration for stable, efficient perovskite solar cells.

One of the primary challenges in commercializing perovskite solar cells (PSCs) is achieving both high power conversion efficiency (PCE) and sufficient stability. We integrate wafer-scale continuous monolayer MoS buffers at the top and bottom of a perovskite layer through a transfer process. These films physically block ion migration of perovskite into carrier transport layers and chemically stabilize the formamidinium lead iodide phase through strong coordination interaction.

RTEL1 is upregulated in gastric cancer and promotes tumor growth.

Gastric cancer (GC) is one of the most common cancers worldwide, with increasing incidence and mortality rates. It is typically diagnosed at advanced stages, leading to a poor prognosis. GC is a highly heterogeneous disease and its progression is associated with complex interplay between genetic and environmental factors.

Capture of Polysulfides Enabled by a Nitrogen-Doped Carbon-Coated Halloysite Nanotube-Modified Separator to Enhance Performance for Lithium-Sulfur Batteries.

Lithium-sulfur (Li-S) batteries stand out as highly promising energy storage systems because of their superior theoretical capacity and the affordability of sulfur as an active material. However, their inherent drawbacks have hindered the commercialization of Li-S batteries. Of these, the polysulfide shuttle effect is one of the most critical issues, leading to the rapid decline in battery capacity.

Ferroptosis and the tumor microenvironment.

Ferroptosis is a type of regulated cell death characterized by its non-apoptotic, iron-dependent and oxidative nature. Since its discovery in 2012, extensive research has demonstrated its pivotal roles in tumorigenesis, metastasis and cancer therapy. The tumor microenvironment (TME) is a complex ecosystem comprising cancer cells, non-cancer cells, extracellular matrix, metabolites and cytokines.

Flexible Highly Thermally Conductive PCM Film Prepared by Centrifugal Electrospinning for Wearable Thermal Management.

Personal thermal management materials integrated with phase-change materials have significant potential to satisfy human thermal comfort needs and save energy through the efficient storage and utilization of thermal energy. However, conventional organic phase-change materials in a solid state suffer from rigidity, low thermal conductivity, and leakage, making their application challenging. In this work, polyethylene glycol (PEG) was chosen as the phase-change material to provide the energy storage density, polyethylene oxide (PEO) was chosen to provide the backbone structure of the three-dimensional polymer network and cross-linked with the PEG to provide flexibility, and carbon nanotubes (CNTs) were used to improve the mechanical and thermal conductivity of the material.

Active site-exposed BiWO@BiOCl heterostructures for photocatalytic hydrogenation of nitroaromatic compounds.

Constructing heterostructured photocatalysts with highly exposed active sites proves to be an efficient strategy to improve the photocatalytic performance of bismuth-based photocatalysts. In this work, active site-exposed BiWO@BiOCl (BWO@BOC) heterostructure composites based on two bismuth-based materials were fabricated by an growth method for improving the photocatalytic hydrogenation of 4-aniline (4-NA) to -phenylenediamine (PPD). BWO@BOC exhibited enhanced photoactivity for 4-NA hydrogenation compared to pure BWO and BOC.

Adsorption Performance of Modified Graphite from Synthetic Dyes Solutions.

Due to the severe harmful impacts of industrial dyeing wastewater on ecosystems and human health, proper treatment is crucial. Herein, the use of modified graphite as an adsorbent for dyeing wastewater treatment was investigated in this study. The graphite was oxidized and intercalated using a phosphoric acid-nitric acid-potassium permanganate system and then thermally treated at high temperatures to optimize its structure.

A novel high-risk model identified by epithelial-mesenchymal transition predicts prognosis and radioresistance in rectal cancer.

Many studies have shown that tumor cells that survive radiotherapy are more likely to metastasize, but the underlying mechanism remains unclear. Here we aimed to identify epithelial-mesenchymal transition (EMT)-related key genes, which associated with prognosis and radiosensitivity in rectal cancer. First, we obtained differentially expressed genes by analyzing the RNA expression profiles of rectal cancer retrieved from The Cancer Genome Atlas database, EMT-related genes, and radiotherapy-related databases, respectively.

Promoting Photon-to-Chemical Conversion through a Dielectric Antenna-Hybrid Bilayered Reactor Configuration.

The application of scattered light via an antenna-reactor configuration is promising for converting thermocatalysts into photocatalysts. However, the efficiency of dielectric antennas in photon-to-chemical conversion remains suboptimal. Herein, we present an effective approach to promote light utilization efficiency by designing dielectric antenna-hybrid bilayered reactors.

Apabetalone, a BET protein inhibitor, inhibits kidney damage in diabetes by preventing pyroptosis via modulating the P300/H3K27ac/PLK1 axis.

Many inflammatory disorders, including diabetic kidney disease (DKD), are associated with pyroptosis, a type of inflammation-regulated cell death. The purpose of this work was to ascertain the effects of apabetalone, which targets BRD4, a specific inhibitor of the bromodomain (BRD) and extra-terminal (BET) proteins that target bromodomain 2, on kidney injury in DKD. This study utilized pharmacological and genetic approaches to investigate the effects of apabetalone on pyroptosis in db/db mice and human tubular epithelial cells (HK-2).

A Study of the Internal Deformation Fields and the Related Microstructure Evolution during Thermal Fatigue Tests of a Single-Crystal Ni-Base Superalloy.

Ni-base superalloys operate in harsh service conditions where cyclic heating and cooling introduce deformation fields that need to be investigated in detail. We used the high-angular-resolution electron backscatter diffraction method to study the evolution of internal stress fields and dislocation density distributions in carbides, dendrites, and notch tips. The results indicate that the stress concentrations decay exponentially away from the notch, and this pattern of distribution was modified by the growth of cracks and the emission of dislocations from the crack tip.

Metformin suppresses gastric cancer progression by disrupting the STAT1-PRMT1 axis.

Gastric cancer (GC) is a common form of cancer and the leading cause of cancer-related deaths worldwide. Chemotherapy is the primary treatment for patients with unresectable or partially resectable GC. However, its adverse effects and chemoresistance greatly restrict its applicability and efficacy.

Exosome secretion related gene signature predicts chemoresistance in patients with colorectal cancer.

Background: Colorectal cancer (CRC) is a highly heterogeneous malignancy, and patients often have different responses to treatment. In this study, the genetic characteristics related to exosome formation and secretion procedure were used to predict chemoresistance and guide the individualized treatment of patients.

Methods: Firstly, seven microarray datasets in Gene Expression Omnibus (GEO) and RNA-Seq dataset from the Cancer Genome Atlas (TCGA) were used to analysis the transcriptome profiles and associated characteristics of CRC patients.

YWHAG promotes colorectal cancer progression by regulating the CTTN-Wnt/β-catenin signaling axis.

Colorectal cancer (CRC) ranks as the third most prevalent cancer type globally. Nevertheless, the fundamental mechanisms driving CRC progression remain ambiguous, and the prognosis for the majority of patients diagnosed at an advanced stage is dismal. YWHA/14-3-3 proteins serve as central nodes in several signaling pathways and are closely related to tumorigenesis and progression.

Global research trends and prospects of cellular metabolism in colorectal cancer.

Background: An increasing number of studies have focused on the role of cellular metabolism in the development of colorectal cancer (CRC). However, no work is currently available to synthesize the field through bibliometrics.

Aim: To analyze the development in the field of "glucose metabolism" (GM), "amino acid metabolism" (AM), "lipid metabolism" (LM), and "nucleotide metabolism" (NM) in CRC by visualization.

Association of dietary live microbe intake with diabetic kidney disease in patients with type 2 diabetes mellitus in US adults: a cross-sectional study of NHANES 1999-2018.

Aims: Several studies have reported dietary microorganisms' beneficial effects on human health. We aimed to detect the potential association between dietary live microbe intake and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM) through a cross-sectional analysis of the National Health and Nutrition Examination Survey from 1999 to 2018.

Methods: According to the Sanders classification system of dietary live microbes, the study participants were divided into three groups: low, medium, and high live microbe groups.

Glycerol-3-phosphate acyltransferase 3-mediated lipid droplets accumulation confers chemoresistance of colorectal cancer.

Colorectal cancer (CRC) is the third most common malignancy worldwide. It is well known that lipid metabolism reprogramming contributes to the tumor progression. However, the lipid metabolic alterations and potential remodeling mechanism underlying the chemoresistance of CRC remain largely unclear.

The association between prenatal bisphenol F exposure and infant neurodevelopment: The mediating role of placental estradiol.

Background: There are limited population studies on the neurodevelopmental effects of bisphenol F (BPF), a substitute for bisphenol A. Furthermore, the role of placental estradiol as a potential mediator linking these two factors remains unclear.

Objective: To examine the association between maternal prenatal BPF exposure and infant neurodevelopment in a prospective cohort study and to explore the mediating effects of placental estradiol between BPF exposure and neurodevelopment in a nested case-control study.

LINC01852 inhibits the tumorigenesis and chemoresistance in colorectal cancer by suppressing SRSF5-mediated alternative splicing of PKM.

Background: Colorectal cancer (CRC) is a major cause of cancer-related deaths worldwide, and chemoresistance is a major obstacle in its treatment. Despite advances in therapy, the molecular mechanism underlying chemoresistance in CRC is not fully understood. Recent studies have implicated the key roles of long noncoding RNAs (lncRNAs) in the regulation of CRC chemoresistance.