Publications by authors named "Zhaohuan Gui"

An increasing proportion of the world's population lives in urban settings that have limited greenspace. Urbanization puts pressure on existing greenspace and reduces its access. Climate impacts, including increased temperature and extreme weather events, challenge the maintenance of urban vegetation, reducing its ecosystem services and benefits for human health.

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Although the effects of ozone and heat on health have been studied independently, the impact of combined exposure remains poorly understood. In this study, C57BL/6 J male mice were individually exposed to ozone (1 ppm), heat (34°C), or both in combination for 4 weeks (5 days/week, 3 h/day). In the Co-exposure group, stress hormones were increased, intensifying the activation of both the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic-adrenal-medullary (SAM) axis.

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Few epidemiological studies have investigated associations between anthropogenic heat emissions (AE) and serum lipids. We recruited 15,477 adults from 33 communities in northeastern China in 2009. We estimated AE flux by using data on energy consumption and socio-economic statistics covering building, transportation, industry, and human metabolism.

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Anthropogenic climate change will have a negative impact on worldwide well-being over and above the direct consequences of rising average temperatures. But anthropogenic heat (AH) relationship with childhood attention deficit hyperactivity disorder (ADHD) is unknown. To assess the relationship with AH exposure and childhood ADHD symptoms in the context of global climate change, this study was conducted in a cross-sectional survey from April 2012 to May 2018 in the northeastern, northwestern, and southern regions of China, with a total enrollment of 179,846 children aged 6-18 years.

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Particulate matter (PM) and contaminants attached to PM can increase the risk of respiratory diseases. However, the health risk assessment of chlorinated paraffins (CPs), an emerging pollutant occupying a high proportion of persistent organic pollutants (POPs) in PM, remains scarce. This study aimed to evaluate the association between PM-bound CPs and asthma, along with relative symptoms, in school-aged children and adolescents.

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Background: Myopia is a pervasive global public health concern, particularly among the younger population. However, the escalating prevalence of myopia remains uncertain. Hence, our research aims to ascertain the global and regional prevalence of myopia, along with its occurrence within specific demographic groups.

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Article Synopsis
  • Metabolic syndrome (MetS) is a growing global health issue, with environmental factors like outdoor artificial light at night (LAN) potentially influencing it.
  • A study involving 15,477 adults examined the impact of LAN on MetS and its components, finding that increased LAN exposure correlated with higher odds of MetS and issues like elevated blood pressure and triglycerides.
  • Notably, individuals who didn't engage in regular exercise were more significantly affected by LAN exposure, indicating that lifestyle factors may modify the risk associated with MetS.
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Evidence on the link of long-term exposure to ozone (O) with childhood asthma, rhinitis, conjunctivitis and eczema is inconclusive. We did a population-based cross-sectional survey, including 177,888 children from 173 primary and middle schools in 14 Chinese cities. A satellite-based spatiotemporal model was employed to assess four-year average O exposure at both residential and school locations.

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Evidence regarding the link between long-term ambient ozone (O) exposure and childhood sleep disorders is little. This study aims to examine the associations between long-term exposure to O and sleep disorders in children. We conducted a population-based cross-sectional survey, including 185,428 children aged 6-18 years in 173 schools across 14 Chinese cities during 2012 and 2018.

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Objectives: Evidence on the link between long-term ambient particulate matter (PM) exposures and childhood sleep disorders were scarce. We examined the associations between long-term exposures to PM and PM (PM with an aerodynamic equivalent diameter <2.5 μm and <1 μm, respectively) with sleep disorders in children.

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Article Synopsis
  • A study with 48,502 Chinese children aged 5-12 explored the link between outdoor Light at Night (LAN) exposure and executive function, using satellite images to assess exposure levels.
  • The results indicated that higher outdoor LAN exposure correlated with poorer executive function and increased risks of executive dysfunction, particularly in older children (ages 10-12).
  • The researchers conclude that reducing outdoor LAN exposure could potentially improve executive function, suggesting the need for further studies on this topic.
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Background And Aims: Engaging in recommended levels of physical activity (PA) is associated with reduced overall and cause-specific mortality rates. Our study aims to examine the relationship between gardening-specific PA and all-cause and cause-specific mortality based on representative U.S.

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Social determinants of health (SDoH) have been linked to a higher likelihood of experiencing mental health problems. This study aimed to investigate whether the accumulation of unfavorable SDoH is associated with depression symptom. Data was gathered from a representative population participating in the U.

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Article Synopsis
  • The study investigates the link between exposure to chlorinated paraffins (CPs), a type of persistent organic pollutant, and the prevalence of allergic diseases in children and adolescents in the Pearl River Delta region of China.
  • A survey with 131,304 participants highlighted that increased levels of CPs in particulate matter are significantly associated with allergic rhinitis, atopic eczema, and allergic conjunctivitis, showing specific odds ratios for each condition.
  • The research suggests that overweight and obese individuals may be at an even higher risk for these allergic diseases; however, further studies are necessary to confirm these findings and explore the underlying mechanisms.
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Background: Limited evidence exists regarding the link between air pollution exposure and cognitive function in developing countries, particularly in areas with abundant natural sources of particulate matter.

Objectives: To investigate this association in a large representative sample of the elderly in northwestern China.

Methods: We performed a cross-sectional study among 176,345 participants aged 60-100 years in northwestern China in 2020.

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Aim: To examine the impact of both individual and cumulative social determinants of health (SDoH) on the likelihood of developing periodontitis, while also exploring any gender disparities in this relationship.

Materials And Methods: Data of self-reported SDoH domains and sub-items based on Healthy People 2030 were obtained from the U.S.

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Information on the spatio-temporal patterns of the burden of ischemic heart disease (IHD) caused by ambient ambient fine particulate matter (PM) in the global level is needed to prioritize the control of ambient air pollution and prevent the burden of IHD. The Global Burden of Disease Study (GBD) 2019 provides data on IHD attributable to ambient PM. The IHD burden and mortality attributable to ambient PM were analyzed by year, age, gender, socio-demographic index (SDI) level, geographical region and country.

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This study examined the associations of long-term exposure to ambient fine particulate matter (PM) compositions/ozone with methylation of peripheral brain-derived neurotrophic factor (BDNF) promoters. A total of 101 participants were recruited from a cohort in Shijiazhuang, Hebei province, China. They underwent baseline and follow-up surveys in 2011 and 2015.

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Anthropogenic heat has been reported to have significant health impacts, but research on its association with childhood adiposity is still lacking. In this study, we matched the 2008-2012 average anthropogenic heat flux, as simulated by a grid estimation model using inventory methods, with questionnaire and measurement data of 49,938 children randomly recruited from seven cities in Northeast China in 2012. After adjusting for social demographic and behavioral factors, we used generalized linear mixed-effect models to assess the association between anthropogenic heat flux and adiposity among children.

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Background: Air pollution exposures are increasingly suspected to influence the development of childhood adiposity, especially focusing on outdoor exposure, but few studies investigated indoor exposure and childhood obesity.

Objectives: We aimed to examine the association between exposure to multiple indoor air pollutants and childhood obesity in Chinese schoolchildren.

Methods: In 2019, we recruited 6499 children aged 6-12 years from five Chinese elementary schools in Guangzhou, China.

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Sugar-sweetened beverages (SSBs) consumption has risen significantly, which may lead to various health problems. Studies about the association between SSBs and attention-deficit/hyperactivity disorder (ADHD) in children are rare and inconsistent. We have used the two-stage cluster sampling method to select 6541 students aged 6-12.

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Background: While increasing studies confirmed the adverse effects of indoor air pollution (IAP) on cardiopulmonary systems, less is known about the impact of IAP on child's brain.

Objective: To explore the associations between multiple indoor air pollutants exposures and attention-deficit/hyperactivity disorder (ADHD) symptoms in Chinese schoolchildren.

Methods: We invited 8630 individuals aged 6-12 years from an ongoing school-based cohort study across Guangzhou from April to May 2019.

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Background: The evidence for associations of emotional/behavioral status with sedentary behavior (SB), physical activity (PA) and step counts is scarce in children with autism spectrum disorder (ASD). Also, ASD-related deficiencies may affect actual levels of PA. We aimed to describe accelerometer-measured SB, PA and step counts in children with ASD, and to examine the associations of emotional/behavioral problems with SB, PA and step counts after assessing associations between accelerometer-measured SB, PA and step counts and ASD-related deficiencies.

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Incense burning is common in Asia including China. Research investigating the association between household incense burning and children's neurodevelopment is scarce. We aimed to examine this association in Chinese children.

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