Bisphenol a influences blastocyst implantation via regulating integrin β3 and trophinin expression levels.

Objective: This study is to investigate effects of bisphenol A (BPA) on the blastocyst implantation in endometrium.

Methods: Pregnant mice were orally administered with BPA. Implantation sites were examined, and serum estrogen level was assayed with ELISA.

[Regulatory Role of Nitric Oxide in Development and Hatching of Mouse Blastocysts].

Objective: To determine the regulatory role and mechanism of nitric oxide (NO) in the development and hatching of mouse blastocysts.

Methods: The Kunming female mice were superovulated and then mated with mature male mice. On the day 2.

Inhibitory effects of preimplantation exposure to bisphenol-A on blastocyst development and implantation.

The effect of preimplantation exposure to bisphenol-A (BPA) on blastocyst development and implantation is investigated. Mice were orally administered with BPA (200, 400, 600, and 800 mg/kg/day) from Day 0.5 to Day 3.

Nitric oxide regulates blastocyst hatching in mice.

Objective: This study is to determine the regulatory role of nitric oxide in mouse blastocyst hatching.

Methods: Kunming female mice were superovulated and then mated with mature male mice. On day 2.

[Histone modifications during spermatogenesis and male infertility].

Many pathological phenomena of male infertility are related to epigenetic changes in male germ cells. Epigenetic regulation during spermatogenesis plays an important role in mitotic/meiotic divisions and spermiogenesis. The histones have various post-translational modifications on different amino acid residues during spermatogenesis.

Effects of 14 single herbs on the induction of caspase-3 in tumor cells: a brief review.

Chinese medicines (CMs) are increasingly being used for the treatment of tumors because of their unique advantages. The induction of tumor cell apoptosis is an important method of tumor treatment. Caspase-3 is a member of the caspase (cysteine aspartic proteinases) family of enzymes, which are the major inducers of apoptosis.

[Effect of the chemically assisted enucleation on the enucleation of sheep oocytes and the development of their reconstructed embryos].

In order to enhance the efficiency of sheep somatic cell nuclear transfer, we used a chemically assisted enucleation with colchicine to study the effects of the concentration of colchicine, the incubation time of oocytes in colchicine and the maturation time of oocytes on the enucleation rates and the development of reconstructed embryos. The results showed that 1) there were no significant differences in the rates of cytoplast protrusion and enucleation between oocytes that were incubated in colchicine (0.4 microg/mL) for 0.

[An experimental study on injury of hippocampus neurons in rats by simulated push-pull maneuver of different degrees].

Objective: To explore the degree of injury and phase of push-pull effect induced by different degrees of push-pull maneuver on hippocampus neurons in rats.

Method: Injury of push-pull maneuver on hippocampus neurons in rats after different degrees of push-pull maneuver were determined by general evaluation of animal model, pathologic examination and electronic microscopy.

Result: 1) General evaluation of animal model: the apoplexy index and the pathological grading increased with the increase of intensity of the push-pull maneuver.