Bilayer MOF nanomachine for precision breast cancer cell fluorescent imaging and therapy.

A bilayer MOF reporter (ZIF-67@FAM-mRNA@ZIF-8) was synthesized, and the ZIF-67 was used as a carrier and fluorescent quencher to connect the FAM reporter through electrostatic adsorption and coordination effect. The ZIF-8 covering the outer layer can improve the stability of the probe and cell permeability, which helps the FAM reporter effectively release. After entering the cancer cells, the acidic environment in the cells induced the decomposition of ZIF-8.

Risk of resistance and the metabolic resistance mechanism of Laodelphax striatellus (Fallén) to cyantraniliprole.

Cyantraniliprole is a highly effective diamide insecticide used to control of Laodelphax striatellus (Fallén). This study aimed to assess the insecticide resistance risk of L. striatellus and its metabolic resistance mechanisms.

Effect of different exposure times and doses of cyantraniliprole on oxidative stress and genotoxicity in earthworms (Eisenia fetida).

Cyantraniliprole, the second generation of diamide insecticides, is widely used to control various pests, which will certainly result in adverse effects on earthworms in soil. In this study, after exposure with six doses of cyantraniliprole (0, 0.5, 1, 2.

A DNA-Au nanomachine activated by dual types of biomarkers for multi-site imaging and gene silencing.

A programmed DNA-Au nanomachine has been constructed to achieve imaging of transmembrane glycoprotein MUC1 and cytoplasmic miRNA-21 and trigger gene silencing therapy. The results of MCF-7 cell-specific imaging and apoptosis experiments demonstrate that the nanomachine provides a valuable nanotheranostic platform for accurate multi-site imaging and intracellular gene silencing.

Sensitivity Differences and Biochemical Characteristics of (Fallén) to Seven Insecticides in Different Areas of Shandong, China.

Fallén is one of the main pests that can severely harm rice, corn, and wheat. Insecticides acting on the nicotinic acetylcholine receptor (nAChR) are the main type of pesticides used for the control of in Shandong Province, a major grain-producing region in China. In this study, the rice seedling dipping method was used to determine the sensitivities of six field populations in Shandong to seven insecticides acting on nAChR.

Rational design of AIE-based fluorescent probes for hypochlorite detection in real water samples and live cell imaging.

As one kind of important disinfectant and reactive oxygen species (ROS), hypochlorite (ClO), plays vital roles in both water treatment and cell homeostasis. In this work, by decorating a series of groups with different electron donating and withdrawing properties on tetraphenylethene (TPE), four aggregation-induced emission (AIE)-based fluorescent probes containing C˭C double bonds as the potential reaction sites named Probe A, B, C and D were constructed, and their sensing performance for ClO was systematically studied. The results showed that the substituents can not only effectively tune the photophysical properties of the probes, but also make a significant impact on their sensing performance for ClO.

[Recent advances in bacterial biodegradation of naphthalene, phenanthrene by bacteria: a review].

Polycyclic aromatic hydrocarbons (PAHs) are toxic pollutants that exist extensively in the environment. Microbial degradation is the main pathway of PAHs eradication in natural environment and therefore is of importance to investigate. Advancement has been made in recent years regarding the PAHs molecular degradation mechanisms in bacteria.