Publications by authors named "Zhaochi Zhai"
The metabolic breakdown of propiconazole by fungi was examined, and it was found that the microbial model (Cunninghamella elegans ATCC36112) efficiently degrades the triazole fungicide propiconazole through the action of cytochrome P450. This enzyme primarily facilitates the oxidation and hydrolysis processes involved in phase I metabolism. We observed major metabolites indicating hydroxylation/oxidation of propyl groups of propiconazole.
View Article and Find Full Text PDFMetabolic pathway of tebuconazole by soil fungus Cunninghamella elegans ATCC36112.
Antonie Van Leeuwenhoek
December 2023
Article Synopsis
- * A study on the metabolism of tebuconazole in Cunninghamella elegans showed that about 98% of it was degraded within 7 days, resulting in five identified metabolites.
- * The study identified cytochrome P450 and flavin-dependent monooxygenase as key enzymes in the metabolic process, providing insights for understanding the toxicological effects and potential bioremediation of tebuconazole.
In this study, the metabolic pathway of the phenylpyrazole insecticide fipronil in Cunninghamella elegans (C. elegans) was investigated. Approximately 92% of fipronil was removed within 5 days, and seven metabolites were accumulated simultaneously.
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