Publications by authors named "Zhaobo Liu"

Dielectric capacitors with ultrahigh power density have emerged as promising candidates for essential energy storage components in electronic and electrical systems. They enable enhanced integration, miniaturization, and lightweight design. However, the development of dielectric materials for cutting-edge energy storage applications has been significantly limited by their low recoverable energy storage density (W) and energy efficiency (η), especially at moderate electric fields.

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Dielectric capacitors possessing high power density and ultrashort discharge time are valuable for high-power energy storage applications. However, achieving high energy storage density remains challenging due to the limited breakdown strength of dielectric ceramics. In this study, inspired by the layered architecture of natural nacre and with the guidance of phase-field simulations, a strategy of constructing a nacre-like layered structure is proposed to improve the breakdown strength and energy storage density of the ceramics.

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Dielectric nanocomposites have garnered significant interest owing to their potential applications in energy storage. However, achieving high energy density (U) and charge/discharge efficiency (η) remains a challenge in their fabrication. In this paper, core-shell structured BaTiO@Polyvinylpyrrolidone (BT@PVP) nanoparticles are prepared, and incorporated into a semi-crystalline polyvinylidene fluoride (PVDF) matrix.

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Multilayer ceramic capacitor as a vital core-component for various applications is always in the spotlight. Next-generation electrical and electronic systems elaborate further requirements of multilayer ceramic capacitors in terms of higher energy storage capabilities, better stabilities, environmental-friendly lead-free, etc., where these major obstacles may restrict each other.

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Polymer dielectrics are crucial for electronic communications and industrial applications due to their high breakdown field strength (E), fast charge/discharge speed, and temperature stability. The upcoming electronic-electrical systems pose a significant challenge, necessitating polymeric dielectrics to exhibit exceptional thermal stability and energy storage capabilities at high temperatures. Here, ultra-high dielectric constant (ɛ) and charge/discharge efficiency (η) of 0.

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-directed 2-fold bromoboration reactions of diynes with BBr have been developed, allowing the access to novel internally BN-doped polycyclic aromatic hydrocarbons from readily available precursors under mild conditions. Computational investigations identified three potential reaction mechanisms, each involving either BBr or [BBr], with low activation barriers ( < 16 kcal/mol) for all pathways. The resulting brominated products can be further functionalized through various cross-coupling protocols, enabling the synthesis of highly luminescent emitters with quantum yield exceeding 90.

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Article Synopsis
  • * A new system called NW-FPNP/uricase (UOX) is proposed for precise UA regulation, using a biocompatible network that responds to UA levels and dynamically balances UA production and breakdown.
  • * This innovative approach aims to improve treatment safety by preventing drug overdoses and avoiding low uric acid levels, representing a significant advancement in managing UA levels effectively.
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Herein, we report a strategy for preparing a novel ternary metal sulfide (TMS) with a yolk-shell structure based on a "penetration-solidification-annealing" method. A series of FeCoNiSG with tunable structure, different morphology and composition was synthesized by adjusting the degree of sulfuration. Due to the synergistical manipulation of rich interface, defects, vacancies and electrical conductivity, as well as the unique yolk-shell structure, the appropriate sulfuration strategy achieved excellent impedance-matching and strong dielectric loss.

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The great potential of KBiTiO (KBT) for dielectric energy storage ceramics is impeded by its low dielectric breakdown strength, thereby limiting its utilization of high polarization. This study develops a novel composition, 0.83KBT-0.

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Objective: Accumulating evidence has indicated that neurodevelopmental defects may underlie the pathophysiology of bipolar disorder (BD). Insulin-like growth factors (IGFs) are a family of neurotrophic factors that are essential for the survival and development of neurons. The present study aims to investigate whether IGF-2 signaling is implicated in the pathophysiological processes of BD.

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The toughening modification of epoxy resin has received widespread attention. The addition of the second-phase resin has a good toughening effect on epoxy resin. In order to investigate the effect of the second-phase resin on the interphase of composites, in this work the interfacial properties of carbon fiber (CF)/epoxy resin with the second-phase resin structure were investigated.

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Purpose: To investigate the expression of interleukin-6 (IL-6) and β-catenin in oral squamous cell carcinoma (OSCC) and its clinicopathological significance.

Methods: The serum IL-6 concentration in 110 OSCC patients and 109 healthy controls were determined by chemiluminescence analysis. IL-6 and β-catenin expression levels in 68 tumor specimens of OSCC patients undergoing surgical treatment and 6 normal mucosal tissues were determined by immunohistochemistry method.

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Although periodontal diseases have been widely reported in patients with juvenile idiopathic arthritis (JIA), their association with JIA remains controversial. This systematic review and meta-analysis aimed to evaluate the association between JIA and periodontal diseases to facilitate oral health management and periodontal disease prevention in JIA patients. We conducted a comprehensive search of Web of Science, Cochrane Library, PubMed, Embase, Chinese Scientific and Technological Journal (VIP) database, Wan Fang Data, China National Knowledge Infrastructure (CNKI), and China Biomedical Literature Database (CBM) up to 30 September 2022, without publication dates or language restrictions.

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The multifactorial evolutionary algorithm (MFEA) is one of the most widely used evolutionary multitasking (EMT) algorithms. The MFEA implements knowledge transfer among optimization tasks via crossover and mutation operators and it obtains high-quality solutions more efficiently than single-task evolutionary algorithms. Despite the effectiveness of MFEA in solving difficult optimization problems, there is no evidence of population convergence or theoretical explanations of how knowledge transfer increases algorithm performance.

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Article Synopsis
  • Olanzapine, an antipsychotic, is being used as part of antiemetic treatment for breast cancer patients experiencing nausea and vomiting from certain chemotherapy regimens.
  • A review of multiple studies found that patients receiving olanzapine showed significantly higher rates of complete response (no vomiting and no rescue medication) and no nausea compared to those receiving a placebo.
  • The findings suggest that olanzapine is an effective and cost-efficient option for managing chemotherapy-induced nausea and vomiting in breast cancer patients.
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A metal- and hypervalent iodine reagent-free electrochemical oxidative dearomatization-induced [5+2] cycloaddition/pinacol rearrangement cascade reaction was described. The electrosynthetic method showed strong tolerance for vinylphenols, ethynylphenols, and allenylphenols, which thus enabled the rapid assembly of diversely functionalized bicyclo[3.2.

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An electrochemical ODI-[5+2] cascade reaction was developed which enables the rapid assembly of diversely functionalized bicyclo[3.2.1]octadienones from sensitive ethynylphenols.

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Background: The majority of patients with hepatocellular carcinoma (HCC) are diagnosed at an advanced stage that excludes them from potentially curative surgical treatment. Lenvatinib is associated with a high objective response rate (ORR) (40.6%) in advanced HCC, indicating the potential for tumor downstaging and conversion to surgical intervention.

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Increasing evidence has shown that abnormal expression of XPO5 is found in many human cancers and acts as an oncoprotein in certain cancers. However, its functional role in hepatocellular carcinoma (HCC) remains unexplored. In our study, we found that XPO5 was highly expressed in HCC, which was associated with SUMO modification.

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Objective: This study aimed to evaluate the individual and combined diagnostic values of serum alpha-fetoprotein (AFP), des-gamma-carboxyprothrombin (DCP), glypican-3 (GPC3) and golgi protein 73 (GP73) in diagnosing hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC).

Methods: Participants from Beijing YouAn Hospital were enrolled and divided into seven groups. Serum was collected and the levels of AFP, GPC3, GP73 and DCP were simultaneously measured with a protein array.

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Objectives: Des-gamma-carboxyprothrombin (DCP) is an important serum biomarker for the clinical screening of hepatocellular carcinoma (HCC). This study aimed to evaluate the value of DCP for the early diagnosis of alpha-fetoprotein (AFP)-negative hepatitis B virus (HBV)-related HCC.

Methods: We retrospectively enrolled patients with AFP-negative HBV-related HCC and benign liver disease.

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The use of propranolol for the treatment of subglottic haemangioma has become hugely popular due to its effectiveness and safety profile. We report a case of 7-month-old boy who presented with stridor and histopathology suggestive of subglottic haemangioma following microlaryngoscopy and bronchoscopy (MLB). However, he did not respond to propranolol treatment.

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Background: Hepatocellular carcinoma (HCC) is the major pathological type of primary liver cancer, one of the leading causes of cancer death worldwide. In addition, the long-term survival rates of HCC still remain low. Therefore, we attempted to identify the potential key genes in the occurrence of HCC by comparing the expression profiles of very early HCC tissue samples with that of chronic cirrhotic tissue samples by integrating the bioinformatics analysis in this study.

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