Hypoglycemic effect of triterpenoid-rich extracts from Euryale ferox shell on normal and streptozotocin-diabetic mice.

The antioxidant effects of the triterpenoid-rich extracts from Euryale ferox shell (ES) have been confirmed in vitro. This study examined whether the triterpenoid-rich extract from ES eases human hyperglycemia and diabetes caused by metabolic disorders. Normal and streptozocin (STZ)-induced diabetic mice were used as controls for the four groups that received the triterpenoid-rich extracts of ES suspended in distilled water orally at doses of 200, 300, 400, 500±2 mg/L.

Hypoglycemic and hypolipidemic effects of a triterpenoid-rich extract from Euryale shell on streptozotocin-induced diabetic mice.

The hypoglycemic and hypolipidemic effects of a triterpenoid-rich extract from the Euryale shell (ES) was analyzed in streptozotocin-induced diabetic mice. Normal and diabetic mice treated with glimepiride were used as negative and positive controls, respectively. Body weight, organ weight index and cholesterol-related lipid profile parameters were observed after 4 weeks.