Publications by authors named "Zhao-zong Fu"
Article Synopsis
- The study investigates how the distribution of cement during percutaneous vertebroplasty affects the risk of refracture in nearby vertebrae.
- The analysis involved 143 patients, comparing 18 who had refractures within a year to 116 who did not, looking at factors such as bone density, cement leakage, and the type of cement distribution.
- Results showed that lower bone mineral density and higher cement leakage correlated with refractures and that a poor cement distribution index increased the risk of adjacent fractures after the procedure.
Study Design: Vertebral endplate tissues were obtained from patients with degenerated lumbar disc classified as Modic type 1 or type 2 and investigated with immunohistochemical staining and the DNA nick end labelling techniques.
Objective: To examine the expression of fas receptor (FasR) and apoptosis in the endplate cells isolated from patients with degenerative disc disease and to see whether they are associated with the pathological change of endplate.
Methods: Fifty-six degenerated lumbar endplate specimens were obtained from the patients with degenerative disc disease categorized as type Modic I or II in magnetic resonance imaging (MRI) and eight nondegenerated specimens as control (vertebra burst fracture patients without degenerative change in MRI) during surgical procedures.
[Biological characteristics of human degenerative vertebral endplate cells].
Nan Fang Yi Ke Da Xue Xue Bao
April 2010
Objective: To observe the morphology and phenotypes of cells extracted from the endplate in the intervertebral discs and identify the factors affecting their biological characteristic.
Methods: The intervertebral disc endplate were digested enzymatically, and the morphology of the obtained cells was examined under light microscope. Immunhistochemical analysis of collagen II and real-time PCR was carried out, and the morphologies, viability, cell growth, apoptosis and chondrocyte matrix production were compared between the cells isolated from the degenerative and normal vertebral endplates.
Objective: To explore the expression of interleukin 18 (IL-18) and prostaglandin E2 (PGE2) and their relationship in the synoviocytes of patients with osteoarthritis (OA).
Methods: The synovial tissues were obtained from 30 OA patients to isolate the synoviocytes for primary culture. The concentrations of IL-18 and PGE2 in the supernatants of synoviocyte culture were measured by enzyme-linked immunosorbent assay (ELISA).