Publications by authors named "Zhao-zhong Cheng"
Article Synopsis
- Self-expandable metallic (SEM) airway stents are used to treat malignant central airway obstructions and this study compares the operation time and safety between the traditional over-the-wire (OTW) stent and a new through-the-scope (TTS) SEM stent.
- A total of 148 patients were enrolled, with 134 analyzed, showing that the TTS group had a significantly shorter operation time compared to the OTW group (104 seconds vs. 252 seconds).
- Although the TTS group had higher efficacy rates and lower rates of complications like granulation and restenosis, these differences did not reach statistical significance.
Accumulated data over the years have suggested that hypoxia inducible factor-1 alpha (HIF-1α) and its downstream vascular endothelial growth factor (VEGF) gene may be linked with chronic obstructive pulmonary disease (COPD). This study aims to investigate the association of HIF-1α and VEGF genetic polymorphisms and their correlated risks with COPD. COPD patients (case group) and healthy individuals (control group) were recruited.
View Article and Find Full Text PDFObjective: This study evaluated the expression level of high mobility group box-B1 (HMGB-1) and matrix metalloproteinase-9 (MMP-9) in non-small cell lung cancer (NSCLC) inmorder to reveal any relation with development and prognosis.
Methods: NSCLC and normal tissues were selected from 30 patients at age of 30- 73, and used for RT-PCR and Western blot analyses of HMGB-1. A total of 100 paraffin embedded NSCLC tissues were also isolated from patients through surgical resection, and used for detection of HMGB-1 by immunohistochemistry.
Objective: To evaluate the incidence of pulmonary embolism in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD).
Methods: Comprehensive searches as of June 2012 were performed in PubMed (1966-), Embase (1974-), Chinese Biomedical Literature Database (1978-), Chinese Journal Full-text Database (1979-) and VIP Database (1989-) for literatures on the incidence of pulmonary embolism in patients with acute exacerbations of COPD. Meta-analysis was conducted with Stata version 11.