Publications by authors named "Zhao-xia Xu"

Objective: To analyze the characteristics of pulse graph parameters in patients with polycystic ovary syndrome (PCOS) varied at different body mass index (BMI) levels and to provide pulse diagnosis basis for syndrome differentiation and treatment of PCOS.

Methods: Pulse graph parameters of 152 patients with PCOS (26 lean patients, 63 patients with moderate weight, and 63 overweight patients) were measured by a Z-BOX pulse meter, and the pulse graph parameters of patients with PCOS varied at different BMI levels were analyzed.

Results: Fine pulse, slippery pulse, and string-like pulse were the most common pulse conditions in patients with PCOS.

View Article and Find Full Text PDF

Objective: Pulmonary nodules (PNs) are one of the imaging manifestations of early lung cancer screening, which should receive more attention. Traditional Chinese medicine believes that voice changes occur in patients with pulmonary diseases. The purpose of this study is to explore the differences in phonetic characteristics between patients with PNs and able-bodied persons.

View Article and Find Full Text PDF

Objective: To investigate the mechanisms through which myocyte large-conductance Ca-activated K (BK) channels mediate the vasodilation effects of melatonin on cerebral arteries (CAs).

Methods: Middle cerebral arteries (MCA) were obtained from 8-week-old male Wistar rats after anaesthetized. Middle cerebral arterial smooth muscle cells were enzymatically isolated.

View Article and Find Full Text PDF

Asthma is a kind of chronic respiratory inflammation, commonly with breathlessness, chest tightness, coughing, recurrent episodes of wheezing and airflow obstruction, severely affecting human health. A variety of immunocytes are involved in this chronic disease. Chinese herbal medicine(CHM) has a long history in the treatment of asthma.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to create a Chinese Medicine diagnostic model for coronary heart disease (CHD) and validate the principles of Chinese Medicine through algorithmic analysis.
  • - Data from 835 CHD patients were collected using various diagnostic tools, and a multi-label learning algorithm called REAL was used to develop the diagnostic model, identifying five key conditions related to heart health.
  • - The model demonstrated effective recognition rates for these conditions, showing that the methods used in Chinese Medicine align with modern data analysis techniques and support its theoretical foundations.
View Article and Find Full Text PDF
Article Synopsis
  • Allogeneic hematopoietic stem cell transplantation is a common and effective treatment for blood-related diseases, reliant on finding HLA-matched donors.
  • A study examined HLA allele and haplotype distributions among 169,995 Chinese individuals, revealing the presence of many distinct alleles and significant regional variations in haplotype frequencies.
  • This research, the first of its kind in China, provides valuable data for improving donor matching processes and contributes to understanding genetic diversity across different regions in the country.
View Article and Find Full Text PDF

Objective: To analyze the diagnostic consistency of Chinese medicine (CM) specialists in patients with cardiovascular disease and to study syndrome classification and identification based on the multi-label learning method.

Methods: Using self-developed CM clinical scales to collect cases, inquiry information, complexity, tongue manifestation and pulse manifestation were assessed. The number of cases collected was 2,218.

View Article and Find Full Text PDF

During our systematic study on the anticancer activities of Scutellaria barbata, scutebarbatine A (SBT-A), one of the major alkaloids in S. barbata, was found to have antitumor effects on A549 cells. Thus, we designed the present study to investigate in detail the antitumor effects of SBT-A.

View Article and Find Full Text PDF

This study was conducted to illustrate that nonlinear dynamic variables of Traditional Chinese Medicine (TCM) pulse can improve the performances of TCM Zheng classification models. Pulse recordings of 334 coronary heart disease (CHD) patients and 117 normal subjects were collected in this study. Recurrence quantification analysis (RQA) was employed to acquire nonlinear dynamic variables of pulse.

View Article and Find Full Text PDF

Systemic lupus erythematosus (SLE) is an autoimmune disease, with multiple genetic and environmental factors involving in its etiology. Angiotensin converting enzyme (ACE) gene was reported to have important roles in the development and progression of SLE. In this study, a case-control study was carried out to investigate the effects of seven SNPs and I/D in ACE gene in the development of SLE in Northern China.

View Article and Find Full Text PDF

Background. In Traditional Chinese Medicine (TCM), most of the algorithms are used to solve problems of syndrome diagnosis that only focus on one syndrome, that is, single label learning. However, in clinical practice, patients may simultaneously have more than one syndrome, which has its own symptoms (signs).

View Article and Find Full Text PDF

Numerous researchers have taken the solid step forward towards the objectification research of Traditional Chinese Medicine (TCM) four diagnostic methods. However, it is deficient in studies on information fusion of the four diagnostic methods. We establish four-diagnosis syndrome differentiation model of TCM based on information fusion technology.

View Article and Find Full Text PDF

In this paper, factors contributing to the formation of pulse wave were analyzed based on hemodynamic principles. It is considered that formation of pulse wave was related to its propagation and reflection characteristics. Propagation of the pulse wave was characterized by pulse wave velocity, and reflection of the pulse wave was characterized by reflection coefficient.

View Article and Find Full Text PDF

Objective: To develop an inquiry scale for diagnosis of heart system syndromes, and to discuss the provisional standardization of the inquiry method in traditional Chinese medicine (TCM).

Methods: Based on scale-making method, Chinese medicine theory and literature searching, an inquiry scale for diagnosis of heart system syndromes in TCM was developed. Statistics method, frequency counting and Delphi method were used for analysis.

View Article and Find Full Text PDF