Publications by authors named "Zhao-rui Yang"

Article Synopsis
  • Traumatic colon injury (TCI) leads to high mortality rates, and this study aimed to understand its underlying mechanisms and improve survival outcomes in affected individuals.
  • A model using C57BL/6 mice was created to examine microbiota imbalances and protein expression changes, revealing that specific pathogenic bacteria surged and certain proteins, like SERPINA3N, were overexpressed after TCI.
  • The research highlighted that using melatonin (MLT) could lower SERPINA3N levels and enhance survival by restoring gut health, suggesting it could be a promising treatment for TCI patients.
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Background: Totally laparoscopic gastrectomy (TLG) entails both gastrectomy and gastrointestinal reconstruction under laparoscopy. Compared with laparoscopic assisted gastrectomy (LAG), TLG has been demonstrated in many studies to require a smaller surgical incision, result in a faster postoperative recovery and less pain and have comparable long-term efficacy, which has been a research hotspot in recent years. Whether TLG is equally safe and feasible for elderly patients remains unclear.

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Light is the main source for plants to obtain energy.Asarum forbesii is a typical shade medicinal plant, which generally grows in the shady and wet place under the bushes or beside the ditches.It can grow and develop without too much light intensity.

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Background: Traumatic colon injury (TCI) is a common disease during wartime. Prolongation of posttraumatic survival time is an effective approach to patient outcome improvement. However, there is a lack of basic research in this field.

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Background: Neoadjuvant chemotherapy (NACT) combined with surgery is regarded as an effective treatment for advanced gastric cancer (AGC). Laparoscopic surgery represents the mainstream of minimally invasive surgery. Currently, surgeons focus more on surgical safety and oncological outcomes of laparoscopic gastrectomy after NACT.

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Human pituitary tumor-transforming gene 1 (PTTG1) is a newly identified proto-oncogene, and its overexpression occurs in a wide variety of human cancers. The tumor suppressor gene phosphatase and tensin homolog deleted from chromosome 10 (PTEN) is frequently mutated or deleted in numerous tumors, especially in endometrial carcinoma. The aim of this study was to investigate whether the aberrant expression of PTTG1 and PTEN is associated with tumorigenesis and progression of endometrial carcinoma.

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Objective: To evaluate the relationship of hypoxia-inducible factor (HIF)-1alpha expression with chemotherapy response in gastric cancer and its clinical outcome.

Methods: Leucovorin (CF) and 5-fluorouracil (5-FU) in combination with oxaliplatin (L-OHP) were used in 52 patients with gastric carcinoma (GC) at advanced stage. CF 200 mg/m(2) was intravenous drop for 2 h at day 1 and day 14.

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Background & Objective: Notch homolog 1 (Notch1) belongs to the Notch family of transmembrane receptors and plays an important role in cell differentiation. Notch1 plays a profound role in carcinogenesis and can be both oncogenic and tumor suppressive. However, the correlation of Notch1 expression to clinicopathologic features of gastric cancer is unclear.

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Background: The most common complications after liver transplantation are acute and chronic rejection. Although special changes can be found clinically and pathologically in both of them, sometimes other complications such as preservation injury, recurrent disease (HBV) and hepatic artery thrombosis should be differentiated from them.

Methods: Five patients with various complications after liver transplantation were synthetically analyzed according to their clinical information, laboratory tests and liver biopsy findings so as to find out the clinical rules and the histological features.

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