Publications by authors named "Zhao-qi Peng"

Article Synopsis
  • The study focuses on enhancing the prediction of esophageal variceal bleeding (EVB) in cirrhosis patients through a radiomics approach that uses multi-organ data rather than relying on a single imaging level.
  • Researchers evaluated 208 cirrhosis patients, dividing them into training and validation groups, and extracted radiomic features from key organs: liver, spleen, and lower esophagus-gastric fundus.
  • The resulting radiomics-clinical model (RC model) showed superior predictive ability for EVB risk, identifying ascites, portal vein thrombosis, and plasma prothrombin time as significant clinical risk factors, achieving high area under the curve (AUC) values in the training cohort.*
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Ethnopharmacological Relevance: Mu-Xiang-You-Fang (MXYF) is a classic prescription of Hui medicine. It is composed of five herbs and has been used to treat ischemic stroke for many years. However, the potential pharmacological mechanisms of MXYF remain unclear.

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Background: Tuberculosis (TB) is a major infectious disease globally. Adequate and proper use of anti-TB drugs is essential for TB control. This study aims to study China's production capacity and sales situation of anti-TB drugs, and to further discuss the potential for China to contribute to global TB control.

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Thirteen compounds were isolated from the ethyl acetate fraction of Crepis crocea by column chromatographies on silica gel, Sephadex LH-20 and semi-preparative HPLC. The structures were elucidated on the basis of spectral analysis as tectorone I (1), 8β- (2-methyl- 2-hydroxy-3-oxobutanoyloxy) -glucozaluzanin C (2), tectoroside (3), luteolin-7-O-glucoside (4), cosmosiin (5), esculetin (6), 3,4-dihydroxybenzaldehyde (7), trans-4-hydroxycinnamic acid (8), Caffeic acid (9), methyl p-hydroxyphenyllactate (10), ethylp- hydroxyphenyllactate (11), cis-3,4-dihydroxy-β-ionion (12). All the compounds, except for compounds 4 and 9, were isolated from this plant for the first time, and tectorone I (1) is a new natural product.

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