Publications by authors named "Zhao-ming Wei"

Currently, scientifically and reasonably specifying carbon emission reduction measures in the context of "double carbon" has become a common concern worldwide. China's administrative divisions have a notable impact on the formulation and implementation of relevant policies. Therefore the carbon emissions must be calculated accurately under China's administrative divisions at different scales.

View Article and Find Full Text PDF

Aim: To describe the distribution of ocular biometrics and to evaluate its associations with refractive error and to assess the contribution from ocular parameters to refractive error among Chinese myopic children.

Methods: This cross-sectional study evaluated subjects aged 8-12y. Keratometry, ocular biometry, and cycloplegic autorefraction were performed on each subject.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to compare the effectiveness and safety of efdamrofusp alfa with aflibercept in treating neovascular age-related macular degeneration (nAMD) through a randomized phase II trial involving 231 participants.
  • - Participants received either efdamrofusp alfa or aflibercept, with treatments administered monthly for the first three doses and then every eight weeks, measuring visual acuity changes over 52 weeks.
  • - Results showed that efdamrofusp alfa was as effective as aflibercept in improving vision, with similar rates of adverse effects, establishing its noninferiority in treatment outcomes.
View Article and Find Full Text PDF

Aim: To introduce the macular hole (MH) hydromassage technique as a potentially beneficial approach for the treatment of large or persistent MH.

Methods: This retrospective observational case series comprised 16 consecutive patients (17 eyes) diagnosed with MH. Inclusion criteria involved a hole aperture diameter larger than 600 µm or the presence of an unclosed MH larger than 600 µm following the previous vitrectomy.

View Article and Find Full Text PDF

Background: Endophthalmitis occurring in silicone oil-filled eyes is a very rare occurrence, with reported incidence rates ranging between 0.07% and 0.039%.

View Article and Find Full Text PDF

Background In mainland China, patients with neovascular age-related macular degeneration (nAMD) have approximately an 40% prevalence of polypoidal choroidal vasculopathy (PCV). This disease leads to recurrent retinal pigment epithelium detachment (PED), extensive subretinal or vitreous hemorrhages, and severe vision loss. China has introduced various treatment modalities in the past years and gained comprehensive experience in treating PCV.

View Article and Find Full Text PDF

Aim: To investigate changes of choroidal thickness (ChT) in children with myopia and the effect of current myopia control interventions on ChT.

Methods: Major literature databases were searched for studies relevant to myopia in children. All studies used swept-source optical coherence tomography (SS-OCT) or enhanced depth imaging optical coherence tomography (EDI-OCT) to measure the ChT value.

View Article and Find Full Text PDF

Purpose: This study investigated the correlation between corneal biomechanical parameters and the speed of myopia progression.

Methods: This is a retrospective, multicenter study. Both Chinese and Caucasian children were involved.

View Article and Find Full Text PDF

Background: We describe a case of relentless placoid chorioretinitis (RPC) that progressed despite administration of peribulbar and systemic corticosteroids, and was resolved by systemic combined with intravitreal methotrexate.

Case Summary: A 16-year-old male reported painless blurred vision and a temporal scotoma in his right eye for one week. Due to widespread distribution and continuous enlargement, multimodal imaging of the lesions led to the diagnosis of RPC.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to compare ultra-widefield swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA) for detecting diabetic retinopathy (DR) lesions in patients.
  • It involved 23 patients with DR and 23 healthy controls, analyzing parameters like fovea avascular zone (FAZ) size and microaneurysm count using both imaging techniques.
  • The results showed that while SS-OCTA and FA provided similar measurements for some parameters, SS-OCTA showed fewer microaneurysms than FA, suggesting it is a reliable and noninvasive alternative for assessing DR microvasculature.
View Article and Find Full Text PDF

Aim: To evaluate the outcomes of intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents for patients with retinal vein occlusion (RVO) related-macular edema (ME) in Tibetan.

Methods: A retrospective, observational, single-center study. The demographic and clinical data of 90 RVO Tibetan patients (93 eyes) treated with either ranibizumab or conbercept in Tibet Autonomous Region People's Hospital from Jan 2018 to December 2019 were collected.

View Article and Find Full Text PDF

Purpose: To evaluate capillaries perfusion and retinal nerve fiber layer (RNFL) thickness diurnal changes of macular/optic disc regions among participants with or without obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence tomography angiography (OCTA).

Methods: In this study, we enrolled a cohort of 35 participants including 14 patients with mild-to-moderate OSA, 12 patients with severe OSA, and 9 healthy individuals. All participants had Berlin questionnaire filled.

View Article and Find Full Text PDF

Aim: To report an atypical Adams-Oliver syndrome (AOS) family with typical ocular signs of familial exudative vitreoretinopathy (FEVR).

Methods: A patient with visible avascular area and obvious non-perfusion zone in the peripheral retina with systemic signs of AOS was reported. Familial and personal characteristics were collected for the patient and his sister.

View Article and Find Full Text PDF
Article Synopsis
  • A study aimed to identify a new variant of the corticotropin-releasing hormone (CRH) gene that is significant for patients with central serous chorioretinopathy (CSC).
  • Using genetic analysis in families and individual cases, researchers discovered a specific variant (Gln52insPro) in the CRH gene that was linked to CSC in two Chinese families.
  • The variant was found to be strongly associated with CSC in a larger group of Chinese patients, suggesting an important role of the stress response system in the development of CSC and highlighting potential new treatment approaches.
View Article and Find Full Text PDF

To evaluate the safety and efficacy of continuous high-dose (6 mg) intravitreal ganciclovir injections (IVG) for cytomegalovirus (CMV) retinitis (CMVR) after haploidentical hematopoietic stem cell transplantation (Haplo-HSCT), and to explore factors that may influence the treatment procedure. Prospective, randomized, single-blinded, positive-controlled, interventional, comparative study. A total of 22 patients with CMVR (32 eyes) were randomized to either high-dose group (IVG 6 mg weekly) or low-dose group (IVG 3 mg given twice weekly for 2 weeks as induction phase and weekly thereafter as maintenance phase).

View Article and Find Full Text PDF

Aim: To evaluate the two-year outcomes of patients treated for diabetic macular edema (DME) with intravitreal Conbercept (IVC).

Methods: The clinical data of 30 DME patients (36 eyes) were retrospectively reviewed. The patients were treated with IVC for 3mo.

View Article and Find Full Text PDF

Purpose: To evaluate the functional and structural outcomes of intravitreal conbercept monotherapy using a "3 + pro re nata (PRN)" regimen in treatment-naïve subjects with polypoidal choroidal vasculopathy (PCV) up to 12 months.

Methods: Thirty subjects (30 eyes) with PCV participated in this interventional, retrospective study. All subjects received intravitreal injections of 0.

View Article and Find Full Text PDF

Purpose: To compare capillaries perfusion in macular areas at different layers and peripapillary region in radial peripapillary capillaries (RPC) between healthy subjects and subjects with obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence tomography angiography (OCTA).

Methods: Totally 16 eyes with mild-to-moderate OSA, 14 eyes with severe OSA and 22 control eyes were enrolled in this study. Every subject filled out the Berlin questionnaire and received a comprehensive ocular and physical examination.

View Article and Find Full Text PDF

Aim: To explore the process of retinal vascularization and risk factors for retinopathy of prematurity (ROP) treated with intravitreal ranibizumab (IVR) as monotherapy.

Methods: Infants with type 1 ROP who received IVR as primary treatment from August 2014 to October 2016 at Peking University People's Hospital's Ophthalmology Department were included in the study. All eyes received 0.

View Article and Find Full Text PDF

Aim: To describe the involution patterns of vessel growth of retina through fluorescein angiography (FA) of children, who had been under treatment up to 1y previously intravitreal ranibizumab (IVR) as monotherapy for retinopathy of prematurity (ROP).

Methods: This is a retrospective study. The medical information and FA of 17 children (34 eyes) whose area of avascular retina from the ora serrata was more than two disc diameters (DD) were analyzed.

View Article and Find Full Text PDF

Aim: To evaluate the real-life clinical outcomes of intravitreal injection of conbercept combined rescue therapy for polypoidal choroidal vasculopathy (PCV).

Methods: This was an open label, single center, and interventional study. All enrolled patients were treated initially with three consecutive monthly intravitreal conbercept injections (0.

View Article and Find Full Text PDF

The complete sequence of the mitochondrial genome of Podagrion sp. (Hymenoptera: Torymidae) is described. The mitogenome was 15,845 bp in size, and contained typical sets of mitochondrial genes.

View Article and Find Full Text PDF

Aim: To assess the association between endogenous cortisol level and the risk of central serous chorioretinopathy (CSC).

Methods: Case-control studies were systematically searched on PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI) for publishes between January 1990 and July 2017 to assess the association between endogenous cortisol level and CSC. The main endpoints were serum cortisol level at 8 a.

View Article and Find Full Text PDF