Publications by authors named "Zhao-hui Qiu"
Article Synopsis
- The study investigates how liver enzyme levels relate to metabolic syndrome (MetS) risk in older adults, filling a knowledge gap in this demographic.
- It analyzed data from 1,444 seniors and found that higher levels of enzymes like ALT, GGT, and ALP were linked to increased odds of having MetS, while AST showed no significant association.
- The results suggest that monitoring certain liver enzymes could help assess MetS risk in the elderly.
MEF2C loss-of-function mutation associated with familial dilated cardiomyopathy.
Clin Chem Lab Med
February 2018
Background: The MADS-box transcription factor myocyte enhancer factor 2C (MEF2C) is required for the cardiac development and postnatal adaptation and in mice-targeted disruption of the MEF2C gene results in dilated cardiomyopathy (DCM). However, in humans, the association of MEF2C variation with DCM remains to be investigated.
Methods: The coding regions and splicing boundaries of the MEF2C gene were sequenced in 172 unrelated patients with idiopathic DCM.
Sirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice.
Acta Pharmacol Sin
December 2015
Aim: Apolipoprotein E (ApoE) plays an important role in the transport and metabolism of lipids. Recent studies show that bone mass is increased in young apoE(-/-) mice. In this study we investigated the bone phenotype and metabolism in aged apoE(-/-) mice.
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