Synopsis of recent research by authors named "Zhao-cai Yu"
- Zhao-Cai Yu's research primarily focuses on advancing cancer immunotherapy, specifically through the enhancement of dendritic cell (DC)-based vaccines and their impact on hepatitis B virus-related hepatocellular carcinoma. This includes the infection of DCs with specific tumor-associated antigen genes to boost their effectiveness against cancer.
- A significant aspect of Yu's work also explores the role of histone deacetylase inhibitors, such as FK228, in regulating the proliferation and differentiation of human erythroid progenitor cells, which could have implications for cancer treatment and stem cell therapy.
- Additionally, Yu has investigated the development of oral vaccines and bioactive compounds aimed at gastric cancer, focusing on using Salmonella typhimurium as a vector, and peptide screening to identify potential therapeutic targets in gastric cancer-associated antigens.