Publications by authors named "Zhao-Zhao Wu"
[Environment of high temperature or air particle matter pollution, and health promotion of exercise].
Sheng Li Ke Xue Jin Zhan
October 2014
It is important to keep human health in special environment, since the special environment has different effects on health. In this review, we focused on high temperature and air particle matter environment, and health promotion of exercise. Exercise and high temperature are the main non-pharmacological therapeutic interventions of insulin resistance (IR).
View Article and Find Full Text PDF[Mechanism study of adaptive response in high background radiation area of Yangjiang in China].
Zhonghua Yu Fang Yi Xue Za Zhi
September 2010
Article Synopsis
- The study aimed to analyze how local residents in Yangjiang adapt to living in a high background radiation area (HBRA) by examining gene and protein levels of RAGE and S100A6.
- Researchers compared 53 male inhabitants from HBRA with a control group of 53 males from a lower radiation area (Enping), finding significant differences in gene and protein expression levels for RAGE and S100A6.
- The results suggested that lower expression of these markers in the HBRA group may contribute to their adaptive response and lower cancer mortality rates compared to the control group.
Up-regulation of RAGE and S100A6 in rats exposed to cigarette smoke.
Environ Toxicol Pharmacol
September 2009
Article Synopsis
- The study investigated the effects of cigarette smoke on Wistar rats, exposing them to smoke at concentrations of 20% and 60% for 43 weeks to analyze molecular mechanisms related to lung disease.
- Urine samples from the rats were tested for cotinine, a major nicotine metabolite, using HPLC-MS, which showed that cotinine levels could serve as a marker for exposure to cigarette smoke.
- The research found a positive correlation between cotinine levels and the expression of RAGE and S100A6 in the rats' bronchial epithelial cells and lung tissues, suggesting these proteins may play a role in inflammation and oxidative damage linked to cigarette smoke exposure.