Reciprocal regulation of LINC00941 and SOX2 promotes progression of esophageal squamous cell carcinoma.

LINC00941 is a novel long noncoding RNA (lncRNA) and emerging as an important factor in cancer development. However, the exact function and relative regulatory mechanism of LINC00941 in carcinogenesis of esophageal squamous cell carcinoma (ESCC) remain to be further clarified. The present study was to investigate the expression level, functions, and mechanisms of LINC00941 in ESCC tumorigenesis.

Elevated homocysteine and hypertension in Xinjiang Province, China.

Background: Few data are available comparing homocysteine (Hcy) levels in patients with hypertension in different ethnic groups.

Objectives: This study sought to determine whether there are associations of blood pressure and Hcy levels in patients with hypertension from Xinjiang Province, China.

Methods: We examined the serum total Hcy levels in a total of 451 Chinese of various ethnic groups (Han n=234 [51.