Anatomic Surface Measurement of the Lumbar Laminae for Safely Resection During Percutaneous Endoscopic Surgery: A Computed Tomography-Based 3-Dimensional Morphometric Study.

Objective: The aim of this study was to use computed tomography-based 3-dimensional morphometric imaging to precisely quantify the anatomic parameters of the lumbar laminae and increase the precision of laminar fenestration during percutaneous endoscopic spinal surgery.

Methods: Lumbar computed tomography data for the L1-L5 vertebrae of 62 patients (310 total vertebrae) were collected. Laminar width, height, thickness, and bilateral angle were measured in detail, and each parameter was compared and analysed.

Effectiveness of early cervical functional exercise in patients after anterior cervical discectomy and fusion: A randomized controlled trial.

Objective: To observe the effect of early cervical functional exercise (CFE) on clinical outcomes and safety of patients after anterior cervical discectomy and fusion (ACDF).

Methods: Sixty patients who underwent ACDF from September 2019 to September 2020 were analyzed and randomly divided into two groups: the CFE group (27 cases) and the usual care (UC) group (33 cases). Then, all patients in the two groups received routine postoperative guidance care at the same time.

Comparison of the predictive values of MRI-based vertebral bone quality scores for the determination of osteoporosis in different diseases.

Purpose: The study aimed to examine the consistency of vertebral bone quality (VBQ) scores for assessing osteoporosis across different etiologies and explore the predictive value of various VBQ scores for fragility vertebral fractures.

Methods: Patients with fragility fractures were matched by age and sex to patients with lumbar degeneration. VBQ scores were calculated in T1- and T2-weighted magnetic resonance imaging.

VTSNN: a virtual temporal spiking neural network.

Spiking neural networks (SNNs) have recently demonstrated outstanding performance in a variety of high-level tasks, such as image classification. However, advancements in the field of low-level assignments, such as image reconstruction, are rare. This may be due to the lack of promising image encoding techniques and corresponding neuromorphic devices designed specifically for SNN-based low-level vision problems.

Molecular characterization of a cation-dependent mannose-6-phosphate receptor gene in Crassostrea hongkongensis and its responsiveness in Vibrio alginolyticus infection.

The cation-dependent mannose-6-phosphate receptor (CD-M6PR) is a P-type lectin that plays a crucial role in lysosomal enzyme transport, bacterial resistance, and viral entry. In this study, we cloned and analyzed the ORF of the CD-M6PR gene from Crassostrea hongkongensis and named it ChCD-M6PR. We analyzed the nucleotide and amino acid sequence of ChCD-M6PR, its tissue expression pattern and immune response to Vibrio alginolyticus.

Does the sizing of current cervical disc arthroplasty systems match Chinese cervical anatomic dimensions?

The objectives of this study were to analyze the computed tomography (CT) scan imaging data of the cervical spine from healthy volunteers and to correlate the measurements to the dimensions of current cervical disc arthroplasty systems. A total of 130 participants (78 males and 52 females) with a mean age of 41.0 years (range 18.

Ideal entry point and trajectory for C2 pedicle screw placement in children: a 3D computed tomography study.

Purpose: To identify the ideal entry point for pediatric C2 pedicle screw and to obtain parameters of it for the indication of pediatric atlantoaxial fusion arthrodesis.

Methods: The pediatric cervical CT images were reconstructed into the 3D digital models and the C2 vertebrae were separated. The location of ideal entry point and screw placement related linear and angular parameters were assessed on the 3D digital models.

Population pharmacokinetics and dosing optimization of mezlocillin in neonates and young infants.

Objectives: Mezlocillin is used in the treatment of neonatal infectious diseases. However, due to the absence of population pharmacokinetic studies in neonates and young infants, dosing regimens differ considerably in clinical practice. Hence, this study aimed to describe the pharmacokinetic characteristics of mezlocillin in neonates and young infants, and propose the optimal dosing regimen based on the population pharmacokinetic model of mezlocillin.

Baicalein improves cognitive deficits and hippocampus impairments in temporal lobe epilepsy rats.

Temporal lobe epilepsy (TLE) is a chronic neurological disorder that is a refractory disease. Baicalein possesses various pharmacological activities, including neuroprotection in neurodegenerative disease. However, whether baicalein is protective in the treatment of TLE is not determined.