Influences of combined traffic noise on the ability of learning and memory in mice.

Objective: The present study aimed to evaluate the influences of combined traffic noise (CTN) on the ability of learning and memory in mice.

Materials And Methods: The Institute of Cancer Research (ICR) mice were exposed to CTN from highways and high-speed railways for 42 days, whose day-night equivalent continuous A-weighted sound pressure level (L) was 70 dB(A). On the basis of behavioral reactions in Morris water maze (MWM) and the concentrations of amino acid neurotransmitters in the hippocampus, the impacts of CTN on learning and memory in mice were examined.