Publications by authors named "Zhao-Li Zhang"
Article Synopsis
- The study examines how financial toxicity impacts the quality of life (QOL) of lung cancer patients receiving immunotherapy, emphasizing the role of self-perceived burden (SPB).
- A sample of 342 lung cancer patients completed various questionnaires, revealing that higher financial stress correlates with lower QOL, with SPB acting as a mediator in this relationship.
- The findings highlight the need for healthcare providers to assess QOL and financial strains regularly, helping patients navigate their financial decisions related to treatment.
Environmental lipids are essential for fueling tumor energetics, but whether these exogenous lipids transported into cancer cells facilitate immune escape remains unclear. Here, we find that CD36, a transporter for exogenous lipids, promotes acute myeloid leukemia (AML) immune evasion. We show that, separately from its established role in lipid oxidation, CD36 on AML cells senses oxidized low-density lipoprotein (OxLDL) to prime the TLR4-LYN-MYD88-nuclear factor κB (NF-κB) pathway, and exogenous palmitate transfer via CD36 further potentiates this innate immune pathway by supporting ZDHHC6-mediated MYD88 palmitoylation.
View Article and Find Full Text PDFObjectives: To investigate the short-term efficacy and radiotoxicity 3.543of chronoradiotherapy in patients with cervical cancer. We also examined the overall symptom score and quality of life (QOL) of patients who underwent morning radiotherapy and evening radiotherapy.
View Article and Find Full Text PDFBackground: Mindfulness-based stress reduction (MBSR) intervention has been extensively applied in cancer patients for relieving symptom burden and its effectiveness has also been demonstrated. However, the effectiveness of MBSR on psychological and physical functions in lung cancer patients has not yet been determined. The aim of the present systematic review and meta-analysis seeks to determine the role of MBSR in lung cancer patients.
View Article and Find Full Text PDFContext: Trichosanthin produced in the root tube of Trichosanthes kirilowii shows anti-tumor activity on a series of cancer cells including Hela, MCF-7, HL-60. But there is little information about its effect on the carcinogenesis of prostate cancer.
Objective: This work was designed to study the role of trichosanthin on prostate cancer cells PC3.